(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one
- CAS No.
- 126443-09-2
- Chemical Name:
- (2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one
- Synonyms
- ZINC05024189;4'-Amino-4-dimethylaminochalcone;trans-4'-Amino-4-(dimethylamino)chalcone;1-(4-aminophenyl)-3-(4-dimethylaminophenyl)prop-2-en-1-one;(E)-1-(4-aminophenyl)-3-(4-dimethylaminophenyl)prop-2-en-1-one;(2E)-1-(4-Aminophenyl)-3-[4-(dimethylamino)phenyl]-2-propen-1-one;(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one;2-Propen-1-one, 1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]-, (2E)-
- CBNumber:
- CB02131373
- Molecular Formula:
- C17H18N2O
- Molecular Weight:
- 266.34
- MDL Number:
- MFCD00965400
- MOL File:
- 126443-09-2.mol
Melting point | 172 °C |
---|---|
Boiling point | 485.6±45.0 °C(Predicted) |
Density | 1.157±0.06 g/cm3(Predicted) |
pka | 4.50±0.24(Predicted) |
CAS DataBase Reference | 126443-09-2 |
(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Matrix Scientific | 038994 | (2E)-1-(4-Aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one | 126443-09-2 | 500mg | $126 | 2021-12-16 | Buy |
Matrix Scientific | 038994 | (2E)-1-(4-Aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one | 126443-09-2 | 1g | $197 | 2021-12-16 | Buy |
Matrix Scientific | 038994 | (2E)-1-(4-Aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one | 126443-09-2 | 5g | $678 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0080636 | (2E)-1-(4-AMINOPHENYL)-3-[4-(DIMETHYLAMINO)PHENYL]PROP-2-EN-1-ONE 95.00% | 126443-09-2 | 500MG | $716.1 | 2021-12-16 | Buy |
(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one Chemical Properties,Uses,Production
Preparation
Synthesis of ADAB: 1-(4-aminophenyl)-3-(4-(dimethylamino)phenyl)prop-2-en-1-one (ADAB):
4-aminoacetophenone( 1 g, 6.7 mmol) was suspended in ethanol (20 mL), to the suspension 40% of NaOH and 4-dimethylaminobenzaldeyde(0.904 g, 6.7 mmol) were added and stir this reaction mixture at RT for 16h. After completion of the reaction, the reaction mixture was poured into the 100 mL of ice water and P H is adjusted to 1 by drop wise adding of dil. HCl. The reaction mixture was filtered; the filtrate was neutralized with 5% NaHCO3 and subsequently extracted with CH2Cl2. The organic fraction was concentrated in vacuum under reduced pressure. Yield 1.569 g (86%).
1H NMR (400 MHz, CDCl3) δ, 8.10 (dd, J = 15.6, 8.5 Hz, 2H), 7.98 – 7.69 (m, 1H), 7.59 (dd, J = 8.8, 1.9 Hz, 1H), 7.42 (ddd, J = 15.4, 14.6, 6.7 Hz, 2H), 7.20 – 6.89 (m, 2H), 6.75 (dd, J = 15.5, 8.8 Hz, 2H), 3.26 – 2.91 (m, 6H), 1.64 (s, 2H), 13C NMR (101 MHz, CDCl3) δ 161.34 – 161.14 (m), 130.85 (s), 129.58 (s), 121.45 – 121.25 (m), 111.86 (s), 77.35 (s), 77.03 (s), 76.71 (s), 40.17 (s).
(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one Preparation Products And Raw materials
(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 13183 | 58 |
Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35906 | 56 |
MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4981 | 55 |
Beijing FYF Chemicals Co., Ltd | 18612870288; 18612870288 | 1460285141@qq.com | China | 4957 | 58 |
Yantai Lianhua Technology Co., Ltd | 15552437730 | 1701654643@qq.com | China | 10830 | 58 |
Shandong Libixi Biopharmaceutical Technology Co., Ltd. | 15318973357 | 1460285141@qq.com | China | 3867 | 58 |