(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one C화학적 특성, 용도, 생산

제조 방법

Synthesis of ADAB: 1-(4-aminophenyl)-3-(4-(dimethylamino)phenyl)prop-2-en-1-one (ADAB):
4-aminoacetophenone( 1 g, 6.7 mmol) was suspended in ethanol (20 mL), to the suspension 40% of NaOH and 4-dimethylaminobenzaldeyde(0.904 g, 6.7 mmol) were added and stir this reaction mixture at RT for 16h. After completion of the reaction, the reaction mixture was poured into the 100 mL of ice water and P H is adjusted to 1 by drop wise adding of dil. HCl. The reaction mixture was filtered; the filtrate was neutralized with 5% NaHCO3 and subsequently extracted with CH2Cl2. The organic fraction was concentrated in vacuum under reduced pressure. Yield 1.569 g (86%).
1H NMR (400 MHz, CDCl3) δ, 8.10 (dd, J = 15.6, 8.5 Hz, 2H), 7.98 – 7.69 (m, 1H), 7.59 (dd, J = 8.8, 1.9 Hz, 1H), 7.42 (ddd, J = 15.4, 14.6, 6.7 Hz, 2H), 7.20 – 6.89 (m, 2H), 6.75 (dd, J = 15.5, 8.8 Hz, 2H), 3.26 – 2.91 (m, 6H), 1.64 (s, 2H), 13C NMR (101 MHz, CDCl3) δ 161.34 – 161.14 (m), 130.85 (s), 129.58 (s), 121.45 – 121.25 (m), 111.86 (s), 77.35 (s), 77.03 (s), 76.71 (s), 40.17 (s).

(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one 준비 용품 및 원자재

원자재

준비 용품

(2E)-1-(4-aminophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Henan Alfa Chemical Co., Ltd	+8618339805032	alfa4@alfachem.cn	China	13039	58
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35906	56
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	1014988033@qq.com	China	4986	55
Beijing FYF Chemicals Co., Ltd	18612870288; 18612870288	1460285141@qq.com	China	3925	58
Yantai Lianhua Technology Co., Ltd	15552437730	1701654643@qq.com	China	11359	58
Shandong Libixi Biopharmaceutical Technology Co., Ltd.	15318973357	1460285141@qq.com	China	3629	58