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Turimycin H-5

CAS No.
16846-34-7
Chemical Name:
Turimycin H-5
Synonyms
LM-A1;Turimycin H-5;Kitasamycin A1;3-Deacetyljosamycin;Leucomycin V 4''-(3-methylbutanoate);Leucomycin V, 4B-(3-methylbutanoate);KitasaMycin A1, TuriMycin H5, LeucoMycin V 4-isovalerate
CBNumber:
CB02212106
Molecular Formula:
C40H67NO14
Molecular Weight:
785.96
MDL Number:
MOL File:
16846-34-7.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

Turimycin H-5 Properties

storage temp. Store at -20°C
solubility Soluble in DMSO
form solid
FDA UNII YX09Z4QW5Y

SAFETY

Risk and Safety Statements

Toxicity LD50 intraperitoneal in mouse: 620mg/kg

Turimycin H-5 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20585 Leucomycin A1 ≥99% 16846-34-7 1mg $364 2024-03-01 Buy
Cayman Chemical 20585 Leucomycin A1 ≥99% 16846-34-7 5mg $1184 2024-03-01 Buy
TRC L330323 LeucomycinA1 16846-34-7 1mg $260 2021-12-16 Buy
ApexBio Technology C4182 LeucomycinA1 16846-34-7 5mg $1351 2021-12-16 Buy
American Custom Chemicals Corporation API0011773 LEUCOMYCIN A1 95.00% 16846-34-7 5MG $501.57 2021-12-16 Buy
Product number Packaging Price Buy
20585 1mg $364 Buy
20585 5mg $1184 Buy
L330323 1mg $260 Buy
C4182 5mg $1351 Buy
API0011773 5MG $501.57 Buy

Turimycin H-5 Chemical Properties,Uses,Production

Uses

Leucomycin A1 is a major and potent metabolite from the leucomycin complex.

Uses

Leucomycin A1 is a major metabolite from the leucomycin complex, a family of closely related macrocyclic lactone antibiotics produced by Streptomyces kitasatoensis, discovered in 1953. Leucomycin complex (kitasamycin) is used as an animal health product for control of Gram positive bacteria, Gram negative cocci, leptospira and mycoplasma. Little is known about the activity of individual analogues within the complex as their limited availability has restricted investigation.

Definition

ChEBI: Leucomycin A1 is a macrolide.

Biological Activity

leucomycin a1, a major metabolite extracted from the leucomycin complex, is a major macrocyclic lactone antibiotics produced by streptomyces kitasatoensis.leucomycin a1 is one of the more potent members of leucomycin complex. leucomycin complex (kitasamycin) is effective against a wide spectrum of pathogens, such as gram-positive bacteria, gram-negative cocci, mycoplasma, and leptospira. leucomycin complex has been used as an animal health product for control of gram positive bacteria, gram negative cocci, mycoplasma, and leptospira. until now, little is known about the activity of individual analogues within the complex. at a concentration of 1.56μg/ml, kitasamycin inhibited all isolates of diplococcus pneumonia [2]. each component of leucomycins potently inhibited the growth of gram-positive bacteria and showed not so strong activity against the gram-negative bacteria. each component showed the same tendency towards the antibacterial spectrum [3].

References

[1] hata t, sano y, ohki n, et al. leucomycin, a new antibiotic[j]. the journal of antibiotics, 1953, 6(2): 87-89.
[2] balducci y, bodey g p. in vitro activity of kitasamycin against gram-positive cocci[j]. the journal of antibiotics, 1974, 27(7): 516-519.
[3] omura s, katagiri m, umezawa i, et al. structure-biological activities relationships among leucomycins and their derivatives[j]. the journal of antibiotics, 1968, 21(9): 532-538.

Turimycin H-5 Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC Sciences
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Zhejiang Huida Biotech Co., LTD 0571-0571-89903882 15990081639 sunshixuan@huidabiotech.com China 3705 58
3-Deacetyljosamycin Kitasamycin A1 Leucomycin V 4''-(3-methylbutanoate) LM-A1 Turimycin H-5 KitasaMycin A1, TuriMycin H5, LeucoMycin V 4-isovalerate Leucomycin V, 4B-(3-methylbutanoate) 16846-34-7