ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
- CAS No.
- 108290-86-4
- Chemical Name:
- ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
- Synonyms
- SKL228;ETHYL 2-AMINO-1H-PYRROLE-...;Ethyl 2-Aminopyrrole-3-carboxylate;2-amino-1H-pyridine-3-ethyl formate;Ethyl 2-amino-1H-pyrrol-3-carboxylate;ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE;2-amino-1H-Pyrrole-3-carboxy-lic acid ethyl ester;1H-Pyrrole-3-carboxylicacid, 2-aMino-, ethyl ester;2-amino-1H-Pyrrole-3-carboxylic acid ethyl ester (9CI ACI);1H-Pyrrole-3-carboxylic acid, 2-amino-, ethyl ester (9CI, ACI)
- CBNumber:
- CB02453239
- Molecular Formula:
- C7H10N2O2
- Molecular Weight:
- 154.17
- MDL Number:
- MFCD09953569
- MOL File:
- 108290-86-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Amino-1H-pyrrole-3-carboxylicAcidEthylEster | A629275 | 500mg | $440 |
| Ethyl 2-amino-1H-pyrrole-3-carboxylate 95% | 4H56-1-KP | 250mg | $195 |
| Ethyl 2-amino-1H-pyrrole-3-carboxylate 95% | 4H56-1-KP | 1g | $625 |
| 2-Amino-1H-pyrrole-3-carboxylicacidethylester | X6512 | 5g | $667 |
| 2-Amino-1H-pyrrole-3-carboxylicacidethylester 97+% | AS13337 | 1g | $218 |
| More product size | |||
| Boiling point | 360.5±22.0 °C(Predicted) |
|---|---|
| Density | 1.238±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, protect from light |
| pka | 18.24±0.50(Predicted) |
| Appearance | Light green to green Solid |
| InChI | InChI=1S/C7H10N2O2/c1-2-11-7(10)5-3-4-9-6(5)8/h3-4,9H,2,8H2,1H3 |
| InChIKey | XKJUSNOUOLSNJN-UHFFFAOYSA-N |
| SMILES | N1C=CC(C(OCC)=O)=C1N |
| CAS DataBase Reference | 108290-86-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A629275 | 2-Amino-1H-pyrrole-3-carboxylicAcidEthylEster | 108290-86-4 | 500mg | $440 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H56-1-KP | Ethyl 2-amino-1H-pyrrole-3-carboxylate 95% | 108290-86-4 | 250mg | $195 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H56-1-KP | Ethyl 2-amino-1H-pyrrole-3-carboxylate 95% | 108290-86-4 | 1g | $625 | 2021-12-16 | Buy |
| AK Scientific | X6512 | 2-Amino-1H-pyrrole-3-carboxylicacidethylester | 108290-86-4 | 5g | $667 | 2021-12-16 | Buy |
| Activate Scientific | AS13337 | 2-Amino-1H-pyrrole-3-carboxylicacidethylester 97+% | 108290-86-4 | 1g | $218 | 2021-12-16 | Buy |
ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE Chemical Properties,Uses,Production
Uses
2-Amino-1H-Pyrrole-3-carboxylic acid ethyl ester acts as a reagent in the synthesis of pyrrolo pyrimidines which functions as glucocerebrosidase activators use in treatment of medical disorders.
Synthesis
107-20-0
50551-10-5
108290-86-4
1. Preparation of ethyl 2-amino-1H-pyrrole-3-carboxylate. Ethyl 3-amino-3-iminopropionate (390 mg, 3.0 mmol) was dissolved in ethyl acetate (20 mL) under argon protection with vigorous stirring. Anhydrous chloroacetaldehyde was added rapidly at 22 °C. The reaction mixture was stirred for 10 minutes and then heated to reflux for 20 minutes. Cool to room temperature and filter through a silica gel column (15 g). The residue in the reaction flask was washed several times with ethyl acetate (20 mL x 5) and the filtrates were combined. The filtrate was concentrated under reduced pressure to give 120 mg of light yellow solid product in 47% yield. The product was characterized as follows: 1H NMR (500 MHz, CDCl3) δ (ppm): 7.92 (br, 1H), 6.28 (t, J = 2.8 Hz, 1H), 6.15 (dd, J = 2.0 Hz, 1H), 4.94 (br, 2H), 4.24 (q, J = 7.1 Hz, 2H), 1.33 (t, J = 7.1 Hz, 3H).13C NMR (125 MHz, CDCl3) δ (ppm): 166.5, 145.4, 110.3, 107.5, 94.5, 59.3, 14.7.
References
[1] Journal of Heterocyclic Chemistry, 1986, vol. 23, # 5, p. 1555 - 1560
[2] Patent: WO2017/4408, 2017, A1. Location in patent: Paragraph 0087; 0089; 0090
[3] Patent: WO2016/73891, 2016, A1. Location in patent: Paragraph 00204
[4] Patent: US9447100, 2016, B2. Location in patent: Page/Page column 556; 557
ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| RR Scientific LLC | +86-13917743231 | sales@rrscientific.com | United States | 878 | 58 |
View Lastest Price from ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2020-01-14 | ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
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