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(S)-N-Fmoc-2-(2'-propylenyl)alanine

CAS No.
288617-71-0
Chemical Name:
(S)-N-Fmoc-2-(2'-propylenyl)alanine
Synonyms
Fmoc-alpha-All-D-Ala-OH;FMoc-α-Me-Gly(Allyl)-OH;Fmoc-α-Me-Gly(Allyl)-OH;(S)-N-FMOC-Α-ALLYLALANINE;(S)-N-Fmoc-A-Allylalanine;(S)-N-Fmoc-alpha-allylalanine;Fmoc-(S)-2-(2-propenyl)Ala-OH;Fmoc-(S)-2-(2-propenyl)alanine;(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-alpha-methyl-L-allylglycine
CBNumber:
CB02485702
Molecular Formula:
C21H21NO4
Molecular Weight:
351.4
MDL Number:
MFCD02682444
MOL File:
288617-71-0.mol
Last updated:2023-04-23 13:52:06

(S)-N-Fmoc-2-(2'-propylenyl)alanine Properties

Boiling point 564.3±45.0 °C(Predicted)
Density 1.224
storage temp. Inert atmosphere,Store in freezer, under -20°C
pka 3.81±0.11(Predicted)
form liquid
color pale yellow
InChIKey FNCSRFHDUZYOCR-NRFANRHFSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
TSCA  No

(S)-N-Fmoc-2-(2'-propylenyl)alanine price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H950188 (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylpent-4-enoicacid 288617-71-0 50mg $100 2021-12-16 Buy
Usbiological 278035 Fmoc-alpha-methyl-L-allylglycine 288617-71-0 25mg $333 2021-12-16 Buy
Activate Scientific AS46299 (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylpent-4-enoic acid 97% ee 288617-71-0 1g $383 2021-12-16 Buy
Chem-Impex 29359 Fmoc-α-methyl-L-allylglycine,≥99%(HPLC) ≥99%(HPLC) 288617-71-0 1G $483.39 2021-12-16 Buy
ChemPep 180765 Fmoc-α-Me-Gly(Allyl)-OH 288617-71-0 1g $500 2021-12-16 Buy
Product number Packaging Price Buy
H950188 50mg $100 Buy
278035 25mg $333 Buy
AS46299 1g $383 Buy
29359 1G $483.39 Buy
180765 1g $500 Buy

(S)-N-Fmoc-2-(2'-propylenyl)alanine Chemical Properties,Uses,Production

Uses

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

(S)-N-Fmoc-2-(2'-propylenyl)alanine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
GL Biochem (Shanghai) Ltd.
+86-021-61263370 +86-18901917034 CHINA 3904 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9923 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Hunan Jibang Biological Technology Co., LTD
+8613776644403 sales02@kingboomtech.com China 1806 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
(S)-N-Fmoc-2-(2'-propylenyl)alanine (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid (S)-N-Fmoc-alpha-allylalanine (S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine Fmoc-alpha-methyl-L-allylglycine (S)-N-FMOC-Α-ALLYLALANINE FMoc-α-Me-Gly(Allyl)-OH (S)-N-Fmoc-α-2-n-propenylalanine Fmoc-(S)-2-(2-propenyl)alanine Fmoc-(S)-2-(2-propenyl)Ala-OH Fmoc-alpha-All-D-Ala-OH (2S)-2-(Fmoc-amino)-2-methyl-4-pentenoic acid (S)-N-Fmoc-A-Allylalanine 4-Pentenoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2S)- N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-L-α-allylglycine (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Allyl)-OH (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-enoic acid (S)-N-Fmoc-2-(2'-propenyl)alanine Fmoc-α-Me-Gly(Allyl)-OH (S)-N-Fmoc-2-(2'-propylenyl)alanine 288617-71-0 α-Methyl Amino Acids