ChemicalBook >> CAS DataBase List >>4-AMino-5-Methylpyridin-2-ol
4-AMino-5-Methylpyridin-2-ol
- CAS No.
- 95306-64-2
- Chemical Name:
- 4-AMino-5-Methylpyridin-2-ol
- Synonyms
- 4-AMino-5-Methylpyridin-2(1H)-one;4-amino-5-methyl-1H-pyridin-2-one;4-Amino-2-hydroxy-5-methylpyridine;Degarelix Impurity 4;Finerenone Impurity A;Finerenone Impurity 28;Felodipine Impurity 14;Finerenone intermediate;4-amino-5-methylpyridone;4-AMino-5-Methylpyridin-2-ol
- CBNumber:
- CB02507291
- Molecular Formula:
- C6H8N2O
- Molecular Weight:
- 124.14
- MDL Number:
- MFCD12546373
- MOL File:
- 95306-64-2.mol
Last updated:2024-04-29 14:28:21
| Boiling point | 291.0±33.0℃ (760 Torr) |
|---|---|
| Density | 1.137±0.06 g/cm3 (20 ºC 760 Torr) |
| vapor pressure | 0-0Pa at 20-50℃ |
| Flash point | 129.8±25.4℃ |
| storage temp. | 2-8°C(protect from light) |
| pka | 11.90±0.10(Predicted) |
| LogP | -0.51 at 20℃ and pH6.3 |
| CAS DataBase Reference | 95306-64-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4-AMino-5-Methylpyridin-2-ol price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A617510 | 4-Amino-5-methylpyridin-2(1H)-one | 95306-64-2 | 1g | $120 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA16237 | 4-Amino-5-methyl-2(1H)-pyridinone | 95306-64-2 | 2g | $120 | 2021-12-16 | Buy |
| ChemScene | CS-W022074 | 4-Amino-5-methylpyridin-2-ol ≥98.0% | 95306-64-2 | 5g | $260 | 2021-12-16 | Buy |
| ChemScene | CS-W022074 | 4-Amino-5-methylpyridin-2-ol ≥98.0% | 95306-64-2 | 1g | $63 | 2021-12-16 | Buy |
| AK Scientific | CS-W022074 | 4-Amino-5-methylpyridin-2-ol | 95306-64-2 | 1g | $80 | 2021-12-16 | Buy |
4-AMino-5-Methylpyridin-2-ol Chemical Properties,Uses,Production
Description
4-AMino-5-Methylpyridin-2-ol belongs to the pyridine derivatives and is significantly alkaline. Its alcoholic hydroxyl group can undergo corresponding nucleophilic substitution reactions under alkaline conditions. It can be used as a material in organic synthesis and medicinal chemistry. The intermediate is used for the modification and production of drug molecules. For example, the compound can prepare selective mineralocorticoid receptor (MR) antagonist finerenone, which is used to lower the risk of severe kidney and heart problems.
Uses
4-Amino-5-methylpyridin-2(1H)-one has been used as a reactant for the synthesis of BAY 94-8862, a nonsteroidal antagonist of the mineralocorticoid receptor to be used for the treatment of cardiorenal diseases.
Synthesis
2-Chloro-4-amino-5-methylpyridine, dissolved in ethylene glycol, could be a starting material to synthesize 4-AMino-5-Methylpyridin-2-ol. The crude product could be precipitated by adding hydrochloric acid/methanol solution.
4-AMino-5-Methylpyridin-2-ol Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 253)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zison Pharmaceutical (Shandong) Co., Ltd. | +86-0086-531-88259693 +86-18660188356 | maguanglei@zisonpharm.com | China | 57 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18219 | 58 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 906 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10247 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
View Lastest Price from 4-AMino-5-Methylpyridin-2-ol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-31 | 4-Amino-2-hydroxy-5-methylpyridine
95306-64-2
|
US $0.00-0.00 / kg | 1kg | ≥98% by HPLC | 100kg/month | Zison Pharmaceutical (Shandong) Co., Ltd. | |
 |
2024-05-21 | 4-Amino-5-methyl-2(1H)-pyridinone
95306-64-2
|
US $0.00 / kg | 1kg | 98% | 500kg | Shanghai Joiny Pharmaceutical Co.,LTD | |
 |
2024-05-09 | 4-Amino-2-hydroxy-5-methylpyridine
95306-64-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd |
-
- 4-Amino-2-hydroxy-5-methylpyridine
95306-64-2
- US $0.00-0.00 / kg
- ≥98% by HPLC
- Zison Pharmaceutical (Shandong) Co., Ltd.
-
- 4-Amino-5-methyl-2(1H)-pyridinone
95306-64-2
- US $0.00 / kg
- 98%
- Shanghai Joiny Pharmaceutical Co.,LTD
-
- 4-Amino-2-hydroxy-5-methylpyridine
95306-64-2
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
95306-64-2(4-AMino-5-Methylpyridin-2-ol)Related Search:
4-AMino-5-Methyl-2-(1H)-pyridinone
4-AMino-5-Methylpyridin-2-ol
4-amino-5-methylpyridine-2(1H)-one
2(1H)-Pyridinone, 4-amino-5-methyl-
4-Amino-2-hydroxy-5-methylpyridine
4-AMino-5-Methylpyridin-2(1H)-one
4-amino-5-methyl-1H-pyridin-2-one
4-amino-5-methylpyridone
4-amino-5-methyl-1,2-dihydropyridin-2-one
Finerenone Impurity 28
4-Amino-5-methyl-2-hydroxypyridine
4-amino-5-methylpyridine-2(1H)-on
Degarelix Impurity 4
Finerenone Impurity A
4-Amino-5-methyl-2(1H)-pyridinone (4-Amino-5-methyl-2-pyridinol)
4-Amino-5-methylpyridine-2-ol
Finerenone intermediate
4-AMino-5-Methylpyridin-2Chemicalbook(1H)-one
Felodipine Impurity 14
95306-64-2
Intermediate
95306-64-2