ChemicalBook >> CAS DataBase List >>4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
![4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Structure](CAS/GIF/477845-12-8.gif)
- CAS No.
- 477845-12-8
- Chemical Name:
- 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
- Synonyms
- PIM-1 Inhibitor 2;PIM1 Kinase Inhibitor IV;PIM1 Inhibitor 2,PIM 1 Inhibitor 2;4-(3-(4-chlorophenyl)benzo[c]isoxazol-5-yl)pyrimidin-2-amine;4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine;2-Pyrimidinamine, 4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]-
- CBNumber:
- CB02518918
- Molecular Formula:
- C17H11ClN4O
- Molecular Weight:
- 322.75
- MDL Number:
- MOL File:
- 477845-12-8.mol
Last updated:2023-05-18 11:31:22
| Boiling point | 627.1±65.0 °C(Predicted) |
|---|---|
| Density | 1.398±0.06 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | Soluble to 75 mM in DMSO |
| form | Yellow solid |
| pka | 2.98±0.10(Predicted) |
| FDA UNII | QJ8ZMA6BSL |
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17809 | Pim-1 Inhibitor 2 ≥98% | 477845-12-8 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17809 | Pim-1 Inhibitor 2 ≥98% | 477845-12-8 | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 17809 | Pim-1 Inhibitor 2 ≥98% | 477845-12-8 | 10mg | $153 | 2024-03-01 | Buy |
| Tocris | 3589 | PIM-1Inhibitor2 ≥98%(HPLC) | 477845-12-8 | 50 | $488 | 2021-12-16 | Buy |
| Tocris | 3589 | PIM-1Inhibitor2 ≥98%(HPLC) | 477845-12-8 | 10 | $120 | 2021-12-16 | Buy |
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Chemical Properties,Uses,Production
Uses
Pim-1 Inhibitor 2 acts as a serione/threonine kinase targeting proteins involved in cell proliferation and survical. Potential anti-tumor agent.
Uses
Pim-1 is a serine/threonine kinase that targets proteins involved in cell survival and proliferation and has roles in tumorigenesis. Pim-1 inhibitor 2 is a potent Pim-1 inhibitor (Ki = 91 nM) that targets the ATP-binding kinase hinge region.[Cayman Chemical]
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Preparation Products And Raw materials
Raw materials
Preparation Products
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Suppliers
Global( 27)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Aikon International Limited | 025-58851090 13611564524 | lwan@aikonchem.com | China | 15952 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
PIM-1 Inhibitor 2
PIM1 Kinase Inhibitor IV
4-(3-(4-chlorophenyl)benzo[c]isoxazol-5-yl)pyrimidin-2-amine
PIM1 Inhibitor 2,PIM 1 Inhibitor 2
2-Pyrimidinamine, 4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]-
477845-12-8
C17H11CIN4O