Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>9,11-methane-epoxy Prostaglandin F1α

9,11-methane-epoxy Prostaglandin F1α

9,11-methane-epoxy Prostaglandin F1α Structure
9,11-methane-epoxy Prostaglandin F1α structure
CAS No.
72517-81-8
Chemical Name:
9,11-methane-epoxy Prostaglandin F1α
Synonyms
VGRVXLWYKKBTNM-KQMLLPOFSA-N;9,11-methane-epoxy Prostaglandin F1α;9,11-methane-epoxy Prostaglandin 1α;9,11-methane-epoxy Prostaglandin F1α;9,11-methane-epoxy Prostaglandin 1alpha;9,11-methane-epoxy Prostaglandin F1.alpha.;2-Oxabicyclo[2.2.1]heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-, [1α,4α,5β,6α(1E,3S*)]- (9CI)
CBNumber:
CB02590123
Molecular Formula:
C21H36O4
Molecular Weight:
352.51
MDL Number:
MOL File:
72517-81-8.mol
Last updated:2023-06-08 09:03:08
Request For Quotation

9,11-methane-epoxy Prostaglandin F1α Properties

solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 1 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319-H336
Precautionary statements  P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
2 0

9,11-methane-epoxy Prostaglandin F1α price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007850 9,11-methane-epoxy Prostaglandin F1α ≥96% 72517-81-8 100μg $36 2021-12-16 Buy
Cayman Chemical 10007850 9,11-methane-epoxy Prostaglandin F1α ≥96% 72517-81-8 500μg $162 2021-12-16 Buy
Cayman Chemical 10007850 9,11-methane-epoxy Prostaglandin F1α ≥96% 72517-81-8 1mg $288 2021-12-16 Buy
Product number Packaging Price Buy
10007850 100μg $36 Buy
10007850 500μg $162 Buy
10007850 1mg $288 Buy

9,11-methane-epoxy Prostaglandin F1α Chemical Properties,Uses,Production

Description

Prostaglandin (PG) endoperoxides are intermediates in the biosynthesis of PGs, thromboxanes, and prostacyclin. The endoperoxides, PGH2 and PGG2, induce rapid and irreversible aggregation of human platelets.1 PGH1 and PGG1 are known to contract smooth muscle preparations, but are lacking in aggregatory effects. 9,11-methane-epoxy Prostaglandin F1α (9,11-methane-epoxy PGF1α) is a stable epoxymethano analog of PGH1 that produces a strong and dose-related aggregation of washed rabbit platelets (EC50 = 0.88 μM) and contraction of rabbit aortic strips (EC50 = 0.11 μM).1 9,11-methane-epoxy PGF1α induces contraction of guinea pig tracheas (EC50 = 3.4 μM) with a maximal contraction of about 60% of that caused by a submaximal dose of histamine.

References

1. Morita, A., Nishino, H., Hasegawa, K., et al. Biological activities of prostaglandin H1 analogs Prostaglandins 18(4),529-540(1979).

9,11-methane-epoxy Prostaglandin F1α Preparation Products And Raw materials

Raw materials

Preparation Products

9,11-methane-epoxy Prostaglandin F1α Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Supplier Advantage
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
9,11-methane-epoxy Prostaglandin F1α 9,11-methane-epoxy Prostaglandin 1α VGRVXLWYKKBTNM-KQMLLPOFSA-N 9,11-methane-epoxy Prostaglandin F1.alpha. 9,11-methane-epoxy Prostaglandin 1alpha 2-Oxabicyclo[2.2.1]heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-, [1α,4α,5β,6α(1E,3S*)]- (9CI) 9,11-methane-epoxy Prostaglandin F1α 72517-81-8