DECYLUBIQUINONE
- CAS No.
- 55486-00-5
- Chemical Name:
- DECYLUBIQUINONE
- Synonyms
- DECYLUBIQUINONE;6-decylubiquinone;Decylubiquinone (2,3-Dmdb);2,3-DIMETHOXY-5-METHYL-6-DECYL-1,4-BENZOQUINONE;2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione;2,5-Cyclohexadiene-1,4-dione, 2-decyl-5,6-dimethoxy-3-methyl-
- CBNumber:
- CB0262439
- Molecular Formula:
- C19H30O4
- Molecular Weight:
- 322.44
- MDL Number:
- MFCD00083306
- MOL File:
- 55486-00-5.mol
- MSDS File:
- SDS
| Boiling point | 452.9±45.0 °C(Predicted) |
|---|---|
| Density | 1.02±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 10 mg/ml) |
| form | Neat yellow to orange colored oil. |
| color | Yellow or orange |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| FDA UNII | DP8EJ59CQN |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
DECYLUBIQUINONE price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D7911 | Decylubiquinone ≥97% (HPLC) | 55486-00-5 | 10mg | $122 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7911 | Decylubiquinone ≥97% (HPLC) | 55486-00-5 | 25mg | $242 | 2024-03-01 | Buy |
| Cayman Chemical | 21027 | Decylubiquinone ≥98% | 55486-00-5 | 5mg | $35 | 2024-03-01 | Buy |
| Cayman Chemical | 21027 | Decylubiquinone ≥98% | 55486-00-5 | 10mg | $53 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7911 | Decylubiquinone ≥97% (HPLC) | 55486-00-5 | 100mg | $648 | 2024-03-01 | Buy |
DECYLUBIQUINONE Chemical Properties,Uses,Production
Description
Decylubiquinone (55486-00-5) inhibits the Ca2+?dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration.1?Maximum effect on Ca2+?retention capacity of rat liver mitochondria at 100 μM. Inhibits etoposide-induced apoptosis in in L929 cells at 5 μM via inhibition of cytochrome C release.2?Delays rotenone-induced cardiac dysfunction in a zebrafish model of development and cardiovascular function.3?Substrate for various quinone oxidoreductases.4,5
Uses
Decylubiquinone is inhibits the Ca2+-dependent mitochondrial permeability transition pore (MPTP) and also inhibits etoposide-induced apoptosis.
Definition
ChEBI: 6-decylubiquinone is a member of the class of 1,4-benzoquinones that is 2,3-dimethoxybenzoquinone which has been substituted at positions 5 and 6 by decyl and methyl groups. It has a role as a cofactor. It is functionally related to a 6-decylubiquinol.
General Description
Ubiquinone analog.
References
1) Fontaine?et al. (1998),?A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore; J. Biol. Chem.,?273?25734 2) Karpinich?et al. (2002),?The course of Etoposide-Induced Apoptosis from Damage to DNA and p53 Activation to Mitochondrial Release of Cytochrome c; J. Biol. Chem.,?277?16547 3) Pinho?et al. (2013)?How mitochondrial dysfunction affects zebrafish development and cardiovascular function: an in vivo model for testing mitochondria-targeted drugs; Br. J. Pharmacol.,?169?1072 4) Kunow?et al.?(1994)?F420H2: quinone oxidoreductase from Archaeoglobus fulgidus. Characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters; Eur. J. Biochem.,?223?503 5) Zickermann?et al?(1998)?Analysis of the pathogenic human mitochondria mutation ND1/3460 and mutations of strictly conserved residues in it’s vicinity, using the bacterium Paracoccis denitrificans; Biochemistry,?37?11792
DECYLUBIQUINONE Preparation Products And Raw materials
Raw materials
Preparation Products
DECYLUBIQUINONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Qiao Chemical Science Co., Ltd | 021-58892003 | info@qiaochem.com | China | 5881 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Aikon International Limited | 025-66113011 18112977050 | cb6@aikonchem.com | China | 15495 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |