Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit

CAS No.
Chemical Name:
Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit
Synonyms
Anti-Trem2c;Anti-Trem2b;Anti-Trem2a;Anti-TREM-2;Anti-Trem2 antibody produced in goat;Anti-TREM2 antibody produced in rabbit;Anti-TREM-2 antibody produced in rabbit;triggering receptor expressed on myeloid cells 2;Anti-TREM2 (C-terminal) antibody produced in goat;Anti-Triggering receptor expressed on monocytes 2 antibody produced in rabbit
CBNumber:
CB02889089
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit Properties

storage temp. -20°C
form buffered aqueous glycerol solution

Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB2501170 Anti-Trem2 antibody produced in goat affinity isolated antibody, buffered aqueous solution 100μG $568 2024-03-01 Buy
Sigma-Aldrich ABN1471 Anti-TREM-2 clone, from rabbit, purified by affinity chromatography 25μg $176 2024-03-01 Buy
Sigma-Aldrich SAB2501169 Anti-TREM2 (C-terminal) antibody produced in goat affinity isolated antibody, buffered aqueous solution 100μG $568 2024-03-01 Buy
Sigma-Aldrich ABN1471 Anti-TREM-2 clone, from rabbit, purified by affinity chromatography 100μg $401 2024-03-01 Buy
Usbiological 028613 Triggering Receptor Expressed On Myeloid Cells 2 96Tests $864 2021-12-16 Buy
Product number Packaging Price Buy
SAB2501170 100μG $568 Buy
ABN1471 25μg $176 Buy
SAB2501169 100μG $568 Buy
ABN1471 100μg $401 Buy
028613 96Tests $864 Buy

Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit Chemical Properties,Uses,Production

Uses

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

General Description

TREM2 (triggering receptor expressed on myeloid cells 2) is a transmembrane receptor belonging to the immunoglobulin (Ig) family. It is composed of an extracellular region containing the Ig-like domain and a cytoplasmic tail. It has a transmembrane region of 33 amino acids followed by a cytoplasmic tail. It is expressed on myeloid cells such as, macrophages found in tissue and dendritic cells, on microglial cells in the brain.

Biochem/physiol Actions

TREM2 (triggering receptor expressed on myeloid cells 2) is involved in bacterial phagocytosis and regulation of inflammatory response. Its presence in microglia helps to remove the neural debris i.e. amyloid β peptide (Aβ) on microglia. TREM2 suppresses the ability of microglia to phagocytize Aβ, and disturbs the pro-inflammatory activity of these cells. Parkinson′s disease (PD) is portrayed by the degeneration of dopaminergic neurons, in the substantia nigra standards compacta district of the cerebrum. TREM2 binds specifically to the ligands expressed by these dopaminergic neurons. Likewise, microgliosis is additionally involved in the progress of PD. Hence, TREM2 gene might be linked to susceptibility to PD. p.R47H polymorphism in this gene is identified with increased risk of sporadic amyotrophic sidelong sclerosis. Mutation in TREM2 is also associated with polycystic lipomembranous osteodysplaysia with sclerosing leukoencephalop.

Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-TREM2 antibody produced in rabbit Anti-TREM-2 antibody produced in rabbit Anti-Triggering receptor expressed on monocytes 2 antibody produced in rabbit Anti-Triggering receptor expressed on myeloid cells 2 precursor antibody produced in rabbit Anti-TREM-2 Anti-Trem2a Anti-Trem2b Anti-Trem2c Anti-TREM2 (C-terminal) antibody produced in goat triggering receptor expressed on myeloid cells 2 Anti-Trem2 antibody produced in goat