Cadazolid
- CAS No.
- 1025097-10-2
- Chemical Name:
- Cadazolid
- Synonyms
- CS-2475;ACT179811;Cadazolid;ACT-179811;ACT 179811;Cadazolid (ACT-179811);Cadazolid, 10 mM in DMSO;Testosterone Impurity 44;ACT-179811; ACT 179811; ACT179811; CADAZOLID.;Cadazolid,Antibiotic,inhibit,ACT179811,Bacterial,Inhibitor,ACT 179811
- CBNumber:
- CB03133943
- Molecular Formula:
- C29H29F2N3O8
- Molecular Weight:
- 585.55
- MDL Number:
- MOL File:
- 1025097-10-2.mol
| Product description | Number | Pack Size | Price |
| Cadazolid ≥98% | 23030 | 1mg | $32 |
| Cadazolid ≥98% | 23030 | 5mg | $139 |
| Cadazolid ≥98% | 23030 | 10mg | $243 |
| Cadazolid ≥98% | 23030 | 25mg | $533 |
| Cadazolid 97.44% | CS-6972 | 50mg | $450 |
| More product size | |||
| Boiling point | 832.6±65.0 °C(Predicted) |
|---|---|
| Density | 1.539±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:100.0(Max Conc. mg/mL);170.78(Max Conc. mM) |
| form | A crystalline solid |
| pka | 6.44±0.41(Predicted) |
| color | White to off-white |
| FDA UNII | 2OEA2UN10Y |
| NCI Drug Dictionary | cadazolid |
Cadazolid price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 23030 | Cadazolid ≥98% | 1025097-10-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 23030 | Cadazolid ≥98% | 1025097-10-2 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 23030 | Cadazolid ≥98% | 1025097-10-2 | 10mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 23030 | Cadazolid ≥98% | 1025097-10-2 | 25mg | $533 | 2024-03-01 | Buy |
| ChemScene | CS-6972 | Cadazolid 97.44% | 1025097-10-2 | 50mg | $450 | 2021-12-16 | Buy |
Cadazolid Chemical Properties,Uses,Production
Uses
Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
in vivo
Cadazolid is well tolerated up to 3000 mg given twice daily for 10 days. The most common adverse event is headache, with no observed relationship between dose or treatment duration and adverse events. Plasma concentrations of cadazolid are low. No plasma concentrations >3.3 ng/mL are observed after single doses or >6.9 ng/mL after 10 days of multiple doses. Food increased the mean Cmax from 0.73 to 1.87 ng/mL and mean AUC0–t from 3.13 to 15.69 ng·h/mL after a single 300 mg dose. The increase in systemic exposure to cadazolid across doses is less than dose-proportional. The mean cumulative faecal recovery is 81.0%–93.5%. Urinary recovery of unchanged compound is less than 0.015%[1].
IC 50
Oxazolidinone
References
[1] Baldoni D, et al. Cadazolid, a novel antibiotic with potent activity against Clostridium difficile: safety, tolerability and pharmacokinetics in healthy subjects following single and multiple oral doses. J Antimicrob Chemother. 2014 Mar;69(3):706-14. DOI:10.1093/jac/dkt401
[2] Chilton CH, et al. In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection. J Antimicrob Chemother. 2014 Mar;69(3):697-705. DOI:10.1093/jac/dkt411
Cadazolid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 8510 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
