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Lixisenatide

Lixisenatide
Lixisenatide structure
CAS No.
827033-10-3
Chemical Name:
Lixisenatide
Synonyms
PubChem ID: 131709241
CBNumber:
CB03379910
Molecular Formula:
C215H347N61O65S
Formula Weight:
4858.49038
MOL File:
827033-10-3.mol

Lixisenatide Chemical Properties,Uses,Production

Description

Lixisenatide (also known as AVE0010) is a glucagon-like peptide 1 (GLP-1) analog that received marketing approval in February 2013 from the European Commission for the treatment of type 2 diabetes mellitus (T2DM). GLP-1 mimetics, such as exenatide, liraglutide, and lixisenatide act upon the pancreas to promote glucosedependent insulin secretion and to decrease glucagon secretion. They also act on the gastrointestinal tract to delay gastric emptying thereby reducing glucose load postprandially. GLP-1 is a native peptide that is secreted in the gut in reaction to nutrients, but it has a short (2–3 min) half-life in plasma due to the action of DPP-IV. Several modified GLP-1 analogs confer DPP-IV resistance and prolonged plasma half-life, as demonstrated by exenatide (half-life=2–3 h), which was first isolated and identified from the saliva of Helodermatidae lizards (a.k.a. Gila monster).

Originator

Zealand Pharma A/S (Denmark)

brand name

Lumyxia

Lixisenatide Preparation Products And Raw materials

Raw materials

Preparation Products


Lixisenatide Suppliers

Global( 6)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd
0086-411-39042497
0086-411-39042693 sales@alphabiopharm.com China 921 58
Beijing Yibai Biotechnology Co., Ltd
0086-182-6772-3597
sales03@yibaibiotech.com CHINA 420 58
Alabiochem Tech.Co., Ltd. 13962259467 0512-58900862
0086-512-56765862 sales@alabiochem.com;sales@alabiochem.com China 1025 59
Chengdu Youngshe Chemical Co., Ltd. 17380623303 028-62328193-
Caroline@youngshechem.com China 1663 58
Shenzhen READLINE Technology Co., Ltd. 0755-26659310
0755-26659310 yangjinghua@szreadline.com China 271 58
Hangzhou Xinhai Pharmaceutical Technology Co., Ltd. 13867485072 571-86758863-
0571-86758863 lulu@thinheal.com China 227 58

  • PubChem ID: 131709241
  • 827033-10-3
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