Lixisenatide

Lixisenatide C화학적 특성, 용도, 생산

개요

Lixisenatide (also known as AVE0010) is a glucagon-like peptide 1 (GLP-1) analog that received marketing approval in February 2013 from the European Commission for the treatment of type 2 diabetes mellitus (T2DM). GLP-1 mimetics, such as exenatide, liraglutide, and lixisenatide act upon the pancreas to promote glucosedependent insulin secretion and to decrease glucagon secretion. They also act on the gastrointestinal tract to delay gastric emptying thereby reducing glucose load postprandially. GLP-1 is a native peptide that is secreted in the gut in reaction to nutrients, but it has a short (2–3 min) half-life in plasma due to the action of DPP-IV. Several modified GLP-1 analogs confer DPP-IV resistance and prolonged plasma half-life, as demonstrated by exenatide (half-life=2–3 h), which was first isolated and identified from the saliva of Helodermatidae lizards (a.k.a. Gila monster).

Originator

Zealand Pharma A/S (Denmark)

상표명

Lumyxia

Lixisenatide 준비 용품 및 원자재

원자재

준비 용품

Lixisenatide 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Alpha Biopharmaceuticals Co., Ltd	+86-411-39042497 +8613921981412	sales@alphabiopharm.com	China	886	58
Beijing Yibai Biotechnology Co., Ltd	0086-182-6772-3597	sales04@yibaibiotech.com	CHINA	419	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Shanghai Weiyuxi Biotechnology Co. , Ltd.	+8613917132737	lily.xiang@wayxbio.com	China	242	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58

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