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CALANOLIDE A

CALANOLIDE A Structure
CALANOLIDE A structure
CAS No.
142632-32-4
Chemical Name:
CALANOLIDE A
Synonyms
NSC675451;NSC-675451;NSC 675451;CALANOLIDE A;(+) Calanolide A;(+)-Calanolide A;(10R,11S,12S)-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one;(+)-(10R,11S,12S)-12-HYDROXY-6,6,10,11-TETRAMETHYL-4-PROPYL-11,12-DIHYDRO-2H,6H,10H-BENZO(1,2-B:3,4-B':5,6-B'']TRIPYRAN-2-ONE;2H,6H,10H-Dipyrano[2,3-f:2',3'-h][1]benzopyran-2-one, 11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-, (10R,11S,12S)-;CALANOLIDE A,(+)-(10R,11S，12S)-12-HYDROXY-6,6,10,11-TETRAMETHYL-4-PROPYL-11，12-DIHYDRO-2H，6H,10H-BENZO(1，2-B：3,4-B'：5,6-B ]TRIPYRAN-2-ONE
CBNumber:
CB0377395
Molecular Formula:
C22H26O5
Molecular Weight:
370.44
MDL Number:
MFCD00867485
MOL File:
142632-32-4.mol
Last updated:2023-05-04 17:34:33
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CALANOLIDE A Properties

FDA UNII S5A9TQN46W

CALANOLIDE A price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C125000 (+)-CalanolideA 142632-32-4 10mg $1320 2021-12-16 Buy
American Custom Chemicals Corporation API0010450 (+)-(10R,11S,12S)-12-HYDROXY-6,6,10,11-TETRAMETHYL-4-PROPYL-11,12-DIHYDRO-2H,6H,10H-BENZO(1,2-B:3,4-B':5,6-B'']TRIPYRAN-2-ONE 95.00% 142632-32-4 5MG $501.47 2021-12-16 Buy
Product number Packaging Price Buy
C125000 10mg $1320 Buy
API0010450 5MG $501.47 Buy

CALANOLIDE A Chemical Properties,Uses,Production

Uses

(+)-Calanolide A is an experimental non-nucleoside reverse transcriptase inhibitor. It has potent anti-HIV activity.

Definition

ChEBI: (+)-calanolide A is an organic heterotetracyclic compound that is 11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one substituted by a hydroxy group at position 12, methyl groups at positions 6, 6, 10 and 11 and a propyl group at position 4 (the 10R,11S,12S stereoisomer). Isolated from Calophyllum lanigerum var austrocoriaceum and Calophyllum brasiliense, it exhibits potent activity against HIV-1 reverse transcriptase. It has a role as a HIV-1 reverse transcriptase inhibitor and a plant metabolite. It is an organic heterotetracyclic compound, a delta-lactone, a cyclic ether and a secondary alcohol.

CALANOLIDE A synthesis

108-73-6
142632-32-4
Synthesis of CALANOLIDE A from Phloroglucinol

CALANOLIDE A Preparation Products And Raw materials

Raw materials

2H-1-Benzopyran-2-one, 5,7-dihydroxy-8-(1-oxopropyl)-4-propyl- 2H,8H-Benzo[1,2-b:3,4-b']dipyran-8-one, 5-hydroxy-2,2-dimethyl-6-(1-oxopropyl)-10-propyl- 5 7-DIHYDROXY-4-PROPYLCOUMARIN 98 AIDS033638 (+)-calanolide D
4 4-DIMETHOXY-2-METHYL-2-BUTANOL 97 Ethyl butyrylacetate Phloroglucinol

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Preparation Products

calanolide B

CALANOLIDE A Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
CR Corporation Lomited 		fred.wen@crcorporation.cn CHINA 12069 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 50002 58
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2127 70
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
TaiChem Taizhou Limited 052386810091 zcwy9518@yeah.net China 3871 58
Wuhan FengyaoTonghui Chemical Products Co., Ltd. 027-87466105 15377573527 2678564200@qq.com China 17997 58
Twochem Co.Ltd. 021-58111628 15800915896 China 1988 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
TargetMol Chemicals Inc. 		58
CR Corporation Lomited 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
GIHI CHEMICALS CO.,LIMITED 		58
LGM Pharma 70
Shanghai Kewel Chemical Co., Ltd. 50
TaiChem Taizhou Limited 58
Wuhan FengyaoTonghui Chemical Products Co., Ltd. 58
Twochem Co.Ltd. 58

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CALANOLIDE A (+)-(10R,11S,12S)-12-HYDROXY-6,6,10,11-TETRAMETHYL-4-PROPYL-11,12-DIHYDRO-2H,6H,10H-BENZO(1,2-B:3,4-B':5,6-B'']TRIPYRAN-2-ONE CALANOLIDE A,(+)-(10R,11S，12S)-12-HYDROXY-6,6,10,11-TETRAMETHYL-4-PROPYL-11，12-DIHYDRO-2H，6H,10H-BENZO(1，2-B：3,4-B'：5,6-B ]TRIPYRAN-2-ONE (10R,11S,12S)-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one 2H,6H,10H-Dipyrano[2,3-f:2',3'-h][1]benzopyran-2-one, 11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-, (10R,11S,12S)- (+)-Calanolide A (+) Calanolide A NSC 675451 NSC675451 NSC-675451 142632-32-4