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Phenylpyropene A

Phenylpyropene A structure

CAS No.: 189564-20-3

Chemical Name:: Phenylpyropene A

Synonyms: Phenylpyropene A;(3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-2H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-11-one;2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one, 3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-, (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-

CBNumber:: CB06197858

Molecular Formula:: C32H38O10

Molecular Weight:: 582.64

MDL Number:

MOL File:: 189564-20-3.mol

Last updated:2023-05-21 10:59:17

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Phenylpyropene A Properties

Boiling point	676.9±55.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Residue
pka	11.78±0.70(Predicted)

Phenylpyropene A Chemical Properties,Uses,Production

Description

Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.^1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC₅₀ = 0.8 μM).¹ Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC₅₀ = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.³

References

1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of acyl-CoA: Cholesterol acyltransferase produced by Penicillium griseofulvum F1959 J. Antibiot. (Tokyo) 55(11),1004-1008(2002).
2. Lee, S.W., Rho, M.C., Choi, J.H., et al. Inhibition of diacylglycerol acyltransferase by phenylpyropenes produced by Penicillium griseofulvum F1959 J. Microbiol. Biotechnol. 18(11),1785-1788(2008).
3. Horikoshi, R., Goto, K., Mitomi, M., et al. Identification of pyripyropene A as a promising insecticidal compound in a microbial metabolite screening J. Antibiot. (Tokyo) 70(3),272-276(2017).

Phenylpyropene A Preparation Products And Raw materials

Raw materials

Preparation Products

Phenylpyropene A Suppliers

Global( 9)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8864	58
Zhejiang Huida Biotech Co., LTD	0571-89903882 13626641628	jiangnan@huidabiotech.com	China	3661	58
Zhejiang Huida Biotech Co., LTD	0571-0571-89903882 15990081639	sunshixuan@huidabiotech.com	China	3705	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

Supplier	Advantage
BOC Sciences	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Meng Cheng Technology (Shanghai) Co., LTD	58
Zhejiang Huida Biotech Co., LTD	58
Zhejiang Huida Biotech Co., LTD	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

Phenylpyropene A 2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one, 3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-, (3S,4R,4aR,6S,6aS,12R,12aS,12bS)- (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-2H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-11-one 189564-20-3