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TUMOR NECROSIS FACTOR

TUMOR NECROSIS FACTOR
TUMOR NECROSIS FACTOR structure
CAS No.
Chemical Name:
TUMOR NECROSIS FACTOR
Synonyms
TSG6;α-induced protein 9;α-induced protein 6;TUMOR NECROSIS FACTOR;Anti-TSG6 antibody produced in rabbit;SixTransMembrane protein of prostate 2;Six-transmembrane epithelial antigen of prostate 4
CBNumber:
CB0816188
Molecular Formula:
Formula Weight:
0
MOL File:
Mol file

TUMOR NECROSIS FACTOR Properties

storage temp. 
-20°C

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TUMOR NECROSIS FACTOR Chemical Properties,Uses,Production

General Description

The TNFs (Etanercept, Enbrel) are members of a family ofcytokines that are produced primarily in the innate immunesystem by activated mononuclear phagocytes. Etanercept is a dimeric fusion protein consisting of the extracellularligand-binding portion of the human 75-kDa (p75)TNF receptor (TNFR) linked to the Fc portion of human isotypeIgG1. The Fc component of etanercept contains the CH2domain, the CH3 domain, and the hinge region, but not theCH1 domain of IgG1. These regions are responsible for thebiological effects of immunoglobulins. Each etanerceptmolecule binds specifically to two TNF molecules in the synovialfluid of rheumatoid arthritis patients. It is equally efficaciousat blocking TNFα and TNFβ. The drug is indicatedfor reducing signs and symptoms and inhibiting the progressionof structural damage in patients with moderately toseverely active rheumatoid arthritis. Etanercept is also indicatedfor reducing signs and symptoms of moderately toseverely active polyarticular-course juvenile rheumatoidarthritis in patients 4 years of age and older who have had aninadequate response to one or more disease-modifying antirheumaticdrugs (DMARDS). Etanercept is also indicatedfor reducing signs and symptoms of active arthritis in patientswith psoriatic arthritis.

TUMOR NECROSIS FACTOR Preparation Products And Raw materials

Raw materials

Preparation Products


TUMOR NECROSIS FACTOR Suppliers

Global( 4)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15901 69
Sigma-Aldrich 021-61415566 800-819-3336(Tel) 400-620-3333(Mobile)
021-61415567 orderCN@sial.com China 28780 80

  • TUMOR NECROSIS FACTOR
  • Six-transmembrane epithelial antigen of prostate 4
  • SixTransMembrane protein of prostate 2
  • α-induced protein 9
  • Anti-TSG6 antibody produced in rabbit
  • TSG6
  • α-induced protein 6
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