clofexamide

CAS No.
1223-36-5
Chemical Name:
clofexamide
Synonyms
ANP246;NP-246;IEM-455;ANP 246;ANP-246;clofexamide;Chlofexamide;Amichlophene;2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide;Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]-
CBNumber:
CB0884312
Molecular Formula:
C14H21ClN2O2
Molecular Weight:
284.78
MDL Number:
MFCD00864305
MOL File:
1223-36-5.mol
MSDS File:
SDS
Last updated:2023-07-12 17:21:22

clofexamide Properties

Melting point 45 °C
Boiling point 124.5°C (rough estimate)
Density 1.1742 (rough estimate)
refractive index 1.5200 (estimate)
pka 14.19±0.46(Predicted)
FDA UNII 071P4J77HF

SAFETY

Risk and Safety Statements

Toxicity LD50 oral in rat: 1040mg/kg

clofexamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0011096 CLOFEXAMIDE 95.00% 1223-36-5 5MG $501.37 2021-12-16 Buy
Product number Packaging Price Buy
API0011096 5MG $501.37 Buy

clofexamide Chemical Properties,Uses,Production

Originator

Clofexamide ,CNRS

Manufacturing Process

In 1 L of water there is dissolved 116.0 g (1 mole) of N,Ndiethylethylenediamine and, under vigorous stirring at a temperature maintained below 50°C, there is added 205.0 g (1 mole) of the chloride of pchlorphenoxyacetic acid. The solution becomes rapidly homogeneous; the formation of the basic amide hydrochloride is rapidly completed by further stirring the reaction mixture for 2 h at about 20°C. Then an excess of soda lye is added and the basic amide formed is extracted by ether. The ethereal solution is dried on anhydrous sodium sulfate and ether is distilled after that the residue is dried. So 2-(p-chlorophenoxy)-N-(2-(diethylamino)ethyl) acetamide is obtained.

Therapeutic Function

Antidepressant, Analgesic, Antiinflammatory, Local anesthetic

clofexamide Preparation Products And Raw materials

Raw materials

Preparation Products

clofexamide Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051 1027@dideu.com China 9947 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 780229652@qq.com China 945 58
clofexamide 2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide Amichlophene Chlofexamide IEM-455 NP-246 ANP 246 ANP246 ANP-246 Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]- 1223-36-5