CLOFEZONE
- CAS No.
- 60104-29-2
- Chemical Name:
- CLOFEZONE
- Synonyms
- CLOFEZONE
- CBNumber:
- CB4511715
- Molecular Formula:
- C33H41ClN4O4
- Molecular Weight:
- 593.17
- MDL Number:
- MOL File:
- 60104-29-2.mol
| pka | pKa 4.5(H2O t unde?ned I unde?ned) (Uncertain) |
|---|---|
| FDA UNII | TPT3MH65LD |
| ATC code | M01AA05,M02AA03 |
CLOFEZONE Chemical Properties,Uses,Production
Originator
Perclusone,Anphar-Rolland,France,1967
Manufacturing Process
935 g of phenylbutazone are dissolved, with heating to a lukewarm state, in 2.7 liters of acetone containing 20% water, and the mixture is filtered if necessary. 853.5 g of p-chlorophenoxyacetic acid diethylamino ethylamide are dissolved in 300 cc of acetone containing 20% water, and the solution is poured into the phenylbutazone solution. There is slight heating, and the solution clarifies. The salt crystallizes rapidly. Drying is effected on a Buchner funnel and the mixture is washed in 450 cc of acetone containing 20% of water. The 1,702 g of product obtained is recrystallized in 2,450 cc of acetone containing 20% of water and, after drying in an oven at 37°C, 1,585 g (86%) of product are obtained. The product is in the form of a white crystalline powder having a melting point of from 87° to 89°C in the Maquenne block.
Therapeutic Function
Analgesic, Antiinflammator
CLOFEZONE Preparation Products And Raw materials
CLOFEZONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd | -- | sales@yickvic.com | China | 6214 | 58 |
| Service Chemical Inc. | -- | sales@chemos-group.com | Germany | 6373 | 71 |
| AK Scientific, Inc. | -- | sales@aksci.com | United States | 6357 | 65 |
| Supplier | Advantage |
|---|---|
| Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd | 58 |
| Service Chemical Inc. | 71 |
| AK Scientific, Inc. | 65 |