viloxazine
- CAS No.
- 46817-91-8
- Chemical Name:
- viloxazine
- Synonyms
- viloxazine;2-[(2-Ethoxyphenoxy)methyl]morpholine;Morpholine, 2-[(2-ethoxyphenoxy)methyl]-;Metrifonate Impurity 2-d6(Metrifonate EP Impurity B-d6)(Dichlorvos-d6)
- CBNumber:
- CB0911793
- Molecular Formula:
- C13H19NO3
- Molecular Weight:
- 237.29
- MDL Number:
- MOL File:
- 46817-91-8.mol
- MSDS File:
- SDS
Melting point | 176-179 °C |
---|---|
Boiling point | 379.83°C (rough estimate) |
Density | 1.0942 (rough estimate) |
refractive index | 1.5000 (estimate) |
pka | pKa 8.1 (Uncertain) |
FDA UNII | 5I5Y2789ZF |
ATC code | N06AX09 |
viloxazine Chemical Properties,Uses,Production
Originator
Vivalan,I.C.I. ,UK,1974
Uses
Antidepressant.
Definition
ChEBI: 2-[(2-ethoxyphenoxy)methyl]morpholine is an aromatic ether.
Manufacturing Process
2-Ethoxyphenol is first reacted with epichlorohydrin to give 1,2-epoxy-3-(o-
ethoxyphenoxy)-propane.
A mixture of crude (83%) 1,2-epoxy-3-(o-ethoxyphenoxy)propane (19.4
grams), 70.5 grams 2-aminoethyl hydrogen sulfate, 40.0 grams sodium
hydroxide, 400 ml ethanol and 200 ml water is stirred at 60°C for 18 hours
and is then evaporated to dryness. The residue is dissolved in 200 ml water
and the mixture is extracted three times with 150 ml of diethyl ether each
time. The combined extracts are dried over magnesium sulfate and
evaporated to dryness, The crude product (21.5 grams) is dissolved in
isopropanol (20 ml), 10.5 ml concentrated aqueous hydrochloric acid and 75
ml ethyl acetate are added and the mixture is cooled. The mixture is filtered
and there is thus obtained as solid product 2-(o-ethoxyphenoxymethyl)
morpholine hydrochloride, MP 179° to 182°C (8.6 grams; 38% yield based on
total epoxide used), according to US Patent 3,712,890.
Therapeutic Function
Psychotropic
viloxazine Preparation Products And Raw materials
viloxazine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14350 | 58 |
Qiuxian Baitai New Material Co., LTD | +8618330912755 | sale2@hbyalin.com | China | 1677 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9640 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8672 | 58 |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3581 | 58 |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9977 | 58 |
Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9649 | 58 |
Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6765 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
View Lastest Price from viloxazine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-11-15 | Viloxazine | US $25.00-500.00 / KG | 1KG | 98% | 500ton/Month | Qiuxian Baitai New Material Co., LTD |
- Viloxazine
- US $25.00-500.00 / KG
- 98%
- Qiuxian Baitai New Material Co., LTD