Bis(2-mercaptoethyl) sulfone
- CAS No.
- 145626-87-5
- Chemical Name:
- Bis(2-mercaptoethyl) sulfone
- Synonyms
- Bis(2-thioethyl) sulphone;2,2'-Sulfonylbis-ethanethiol;Ethanethiol, 2,2'-sulfonylbis-;Bis(2-mercaptoethyl) sulphone, 2,2'-Sulphonyldiethanethiol
- CBNumber:
- CB11176170
- Molecular Formula:
- C4H10O2S3
- Molecular Weight:
- 186.32
- MDL Number:
- MOL File:
- 145626-87-5.mol
| Melting point | 57-58°C |
|---|---|
| Boiling point | 375.6±27.0 °C(Predicted) |
| Density | 1.296±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | solid |
| pka | pKa (aqueous soln at 25°): 7.9, 9.0 |
| color | Pale yellow |
| Stability | Moisture Sensitive |
| CAS DataBase Reference | 145626-87-5 |
| FDA UNII | 296JAR8KSL |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| HS Code | 2930909899 |
Bis(2-mercaptoethyl) sulfone price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B482500 | Bis(2-mercaptoethyl)sulfone | 145626-87-5 | 1g | $310 | 2021-12-16 | Buy |
| AK Scientific | 1514CH | Bis(2-mercaptoethyl)sulfone | 145626-87-5 | 500mg | $441 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18676 | Bis(2-mercaptoethyl)sulfone | 145626-87-5 | 1g | $460 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 7507 | Bis(2-mercaptoethyl)sulfone | 145626-87-5 | 1g | $830 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 7507 | Bis(2-mercaptoethyl)sulfone | 145626-87-5 | 5G | $1640 | 2021-12-16 | Buy |
Bis(2-mercaptoethyl) sulfone Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
Bis(2-mercaptoethyl) sulfone is a useful reagent for the reduction of disulfides in aquous solutions. It is a superior substitute for DTT.
Uses
Reagent for reduction of disulfide bonds in aqueous solutions.
Purification Methods
BMS recrystallises from hexane as white fluffy crystals. Large amounts are best recrystallised from de-oxygenated H2O (charcoal). It is a good alternative reducing agent to dithiothreitol. Its IR (film) has 2995, 2657, 1306, 1248, 1124 and 729 cm-1 . The synthetic intermediate thioacetate has m 82-83o (white crystals from CCl4). The disulfide is purified by flash chromatography on SiO2 and elution with 50% EtOAc/hexane and recrystallised from hexane, and has m 137-139o. [Lamoureux & Whitesides J Org Chem 58 633 1993, Beilstein 1 IV 2455.]
Bis(2-mercaptoethyl) sulfone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 4550 | 62 |
| Hunan Waybel Advanced Materials Co.,Ltd | 0745-2866851 19374576088 | 3002708854@qq.com | China | 438 | 60 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | rose.shi@synzest.com | China | 9287 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 18351873721 | helen.zhang@synzest.com | China | 8298 | 58 |
| Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6018 | 58 |