ChemicalBook >> CAS DataBase List >>Forphenicine

Forphenicine

CAS No.
57784-96-0
Chemical Name:
Forphenicine
Synonyms
Forphenicine;L-(+)-Forphenicin;α-Amino-4-formyl-3-hydroxybenzeneacetic acid;Benzeneacetic acid, α-amino-4-formyl-3-hydroxy-, (αS)-
CBNumber:
CB11178811
Molecular Formula:
C9H9NO4
Molecular Weight:
195.17
MDL Number:
MOL File:
57784-96-0.mol
Last updated:2023-07-12 16:45:27

Forphenicine Properties

Boiling point 419.4±45.0 °C(Predicted)
Density 1.485±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 1.62±0.10(Predicted)
form A solid

Forphenicine Chemical Properties,Uses,Production

Biological Activity

Forphenicine is a bacterial metabolite that has been found in S. fulvoviridis and an inhibitor of alkaline phosphatase (IC50 = 0.036 μg/ml for the chicken intestine enzyme).1 It inhibits the growth of HL-60 leukemia cells when used at a concentration of 10 μM.2 Forphenicine (50 and 500 μg/animal) increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).3

References

1.Aoyagi, T., Yamamoto, T., Kojiri, K., et al.Forphenicine, and inhibitor of alkaline phosphatase produced by actinomycetesJ. Antibiot. (Tokyo)31(3)244-246(1978) 2.Miura, K., Sawa, T., Takeuchi, T., et al.Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60J Antibiot (Tokyo)39(5)734-735(1986) 3.Aoyagi, T., Wada, T., Nagai, M., et al.Low-molecular-weight enzyme inhibitors suppress the development of experimental allergic encephalomyelitisExperientia40(12)1405-1407(1984)

Forphenicine Preparation Products And Raw materials

Raw materials

Preparation Products

Forphenicine Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Forphenicine α-Amino-4-formyl-3-hydroxybenzeneacetic acid L-(+)-Forphenicin Benzeneacetic acid, α-amino-4-formyl-3-hydroxy-, (αS)- 57784-96-0