Forphenicine
- CAS No.
- 57784-96-0
- Chemical Name:
- Forphenicine
- Synonyms
- Forphenicine;L-(+)-Forphenicin;α-Amino-4-formyl-3-hydroxybenzeneacetic acid;Benzeneacetic acid, α-amino-4-formyl-3-hydroxy-, (αS)-
- CBNumber:
- CB11178811
- Molecular Formula:
- C9H9NO4
- Molecular Weight:
- 195.17
- MDL Number:
- MOL File:
- 57784-96-0.mol
Forphenicine Chemical Properties,Uses,Production
Biological Activity
Forphenicine is a bacterial metabolite that has been found in S. fulvoviridis and an inhibitor of alkaline phosphatase (IC50 = 0.036 μg/ml for the chicken intestine enzyme).1 It inhibits the growth of HL-60 leukemia cells when used at a concentration of 10 μM.2 Forphenicine (50 and 500 μg/animal) increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).3
References
1.Aoyagi, T., Yamamoto, T., Kojiri, K., et al.Forphenicine, and inhibitor of alkaline phosphatase produced by actinomycetesJ. Antibiot. (Tokyo)31(3)244-246(1978) 2.Miura, K., Sawa, T., Takeuchi, T., et al.Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60J Antibiot (Tokyo)39(5)734-735(1986) 3.Aoyagi, T., Wada, T., Nagai, M., et al.Low-molecular-weight enzyme inhibitors suppress the development of experimental allergic encephalomyelitisExperientia40(12)1405-1407(1984)
Forphenicine Preparation Products And Raw materials
Raw materials
Preparation Products
Forphenicine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ChemeGen 中国 | 18818260767 | sales@chemegen.com | China | 6975 | 58 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
Supplier | Advantage |
---|---|
ChemeGen 中国 | 58 |
Beijing Biocreative Technology Co., Ltd. | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 58 |