MEDICA 16
- CAS No.
- 87272-20-6
- Chemical Name:
- MEDICA 16
- Synonyms
- MEDICA 16;3,3,14,14-TETRAMETHYLHEXADECANEDIOIC ACID;3,3,14,14-TETRAMETHYLHEXADECANEDIONIC ACID;Hexadecanedioic acid, 3,3,14,14-tetramethyl-;ACLY,antidiabetogenic,ATP Citrate Lyase,antidiabetic,skeletal,Inhibitor,MEDICA16,ligands,Free Fatty Acid Receptor,MEDICA-16,insulin,FFAR,endogenous,muscle,inhibit
- CBNumber:
- CB1175406
- Molecular Formula:
- C20H38O4
- Molecular Weight:
- 342.51
- MDL Number:
- MFCD00797684
- MOL File:
- 87272-20-6.mol
| Melting point | 154-159 °C |
|---|---|
| Boiling point | 485.9±18.0 °C(Predicted) |
| Density | 0.984±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: 28 mg/mL |
| pka | 4.51±0.10(Predicted) |
| form | solid |
| color | white |
| FDA UNII | TC257FLPCK |
MEDICA 16 price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M5693 | MEDICA 16 powder, ≥97% (HPLC) | 87272-20-6 | 5mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 90290 | MEDICA 16 ≥98% | 87272-20-6 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 90290 | MEDICA 16 ≥98% | 87272-20-6 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 90290 | MEDICA 16 ≥98% | 87272-20-6 | 10mg | $160 | 2024-03-01 | Buy |
| Cayman Chemical | 90290 | MEDICA 16 ≥98% | 87272-20-6 | 50mg | $684 | 2024-03-01 | Buy |
MEDICA 16 Chemical Properties,Uses,Production
Description
MEDICA 16 is a β,β''-
Uses
MEDICA 16 is a malic enzyme and mitochondrial glycerol-3-phosphate dehydrogenase inducer.
Uses
MEDICA 16 is a β,β'-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol.
Definition
ChEBI: MEDICA 16 is an alpha,omega-dicarboxylic acid that is hexadecanedioic acid carrying methyl groups at positions 3 and 14. It is a free fatty acid 1 (FFA1/GPR40) receptor agonist and an ATP citrate lyase inhibitor, and exhibits hypolipidemic and antidiabetogenic properties. It has a role as an antilipemic drug, an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor, an EC 2.3.3.8 (ATP citrate synthase) inhibitor, a G-protein-coupled receptor agonist and a hypoglycemic agent.
storage
-20°C
MEDICA 16 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9365 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55672 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |