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1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole

CAS No.
331948-99-3
Chemical Name:
1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole
Synonyms
MEPB;1-[2-(4-methylphenoxy)ethyl]-2-(2-phenoxyethylsulfanyl)benzimidazole;1-[2-(4-Methylphenoxy)ethyl]-2-[(2-phenoxyethyl)thio]-1H-benzimidazole;1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole
CBNumber:
CB11883337
Molecular Formula:
C24H24N2O2S
Molecular Weight:
404.52456
MDL Number:
MOL File:
331948-99-3.mol
Last updated:2025-01-27 09:38:02
Product description Number Pack Size Price
MEPB ≥98%(HPLC) SML2455 5mg $84.83
MEPB ≥98%(HPLC) SML2455 25mg $360

1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole Properties

storage temp. -20°C
solubility DMSO: 2mg/mL, clear
form powder
color white to beige
UNSPSC Code 12352200
NACRES NA.77

1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2455 MEPB ≥98%(HPLC) 331948-99-3 5mg $84.83 2025-07-31 Buy
Sigma-Aldrich SML2455 MEPB ≥98%(HPLC) 331948-99-3 25mg $360 2025-07-31 Buy
Product number Packaging Price Buy
SML2455 5mg $84.83 Buy
SML2455 25mg $360 Buy

1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole Chemical Properties,Uses,Production

Biological Activity

MEPB is a modulator of the activation function-2 (AF-2) of the androgen receptor (AR), increasing AR co-repressor binding. MEPB specifically binds the BF3 pocket of the androgen receptor where it modulates binding of co-regulators to the AF2 domain. MEPB was found to rescue degeneration in a mouse model of spinal bulbar muscular atrophy, a motor neuron disease caused by toxic gain of function of the androgen receptor.

1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole Suppliers

Global( 5)Suppliers
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1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole 1-[2-(4-methylphenoxy)ethyl]-2-(2-phenoxyethylsulfanyl)benzimidazole MEPB 1-[2-(4-Methylphenoxy)ethyl]-2-[(2-phenoxyethyl)thio]-1H-benzimidazole 331948-99-3