ESTETROL
- CAS No.
- 15183-37-6
- Chemical Name:
- ESTETROL
- Synonyms
- E 4;UBE4A;ESTETROL;KIAA0126;MGC133315;15α-Hydroxyestriol;15a-Hydroxyestriol;15-ALPHA-HYDROXYESTRIOL;Estra-1,3,5(10)-triene-3,15a,16a,17-tetrol;Estra-1,3,5(10)-triene-3,15α,16α,17β-tetrol
- CBNumber:
- CB1210710
- Molecular Formula:
- C18H24O4
- Molecular Weight:
- 304.38
- MDL Number:
- MFCD00198996
- MOL File:
- 15183-37-6.mol
| Melting point | 233-236°C |
|---|---|
| Boiling point | 491.9±45.0 °C(Predicted) |
| Density | 1.343±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO: soluble20mg/mL, clear |
| form | powder |
| pka | 10.22±0.70(Predicted) |
| color | white to beige |
| optical activity | [α]/D +125 to +135, c = 1 in ethanol |
| FDA UNII | ENB39R14VF |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H362-H351-H360 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313 |
ESTETROL price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1523 | Estetrol ≥98% (HPLC) | 15183-37-6 | 5mg | $219 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1523 | Estetrol ≥98% (HPLC) | 15183-37-6 | 25mg | $870 | 2024-03-01 | Buy |
| Cayman Chemical | 18232 | Estetrol ≥95% | 15183-37-6 | 500μg | $35 | 2021-12-16 | Buy |
| Cayman Chemical | 18232 | Estetrol ≥95% | 15183-37-6 | 1mg | $63 | 2021-12-16 | Buy |
| Cayman Chemical | 18232 | Estetrol ≥95% | 15183-37-6 | 5mg | $158 | 2021-12-16 | Buy |
ESTETROL Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
A metabolite of Estradiol. It is an estrogenic steroid synthesized exclusively by the fetal liver during human pregnancy and reaching the maternal circulation through the placenta.
Uses
Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol and estriol during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ERα over ERβ and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium). In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.
Definition
ChEBI: Estetrol is a 3-hydroxy steroid that is 17beta-estradiol which has been substituted at the 15alpha and 16alpha positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver. It has a role as an estrogen, an estrogen receptor agonist, a human metabolite, a human xenobiotic metabolite and an oral contraceptive. It is a 3-hydroxy steroid, a 17beta-hydroxy steroid, a 16alpha-hydroxy steroid, a 15alpha-hydroxy steroid and a steroid hormone. It derives from a hydride of an estrane.
ESTETROL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Demeikai Biotechnology Co., Ltd | +8618942921723 | info@dmksw.xin | China | 723 | 58 |
| Hubei Harvest Chemical CO.,Ltd | +86-13129915771 +86-15623179893 | wendy@hb-harvestchem.com | China | 931 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Jiangsu shring Biopharma Co., Ltd. | +8613372282299 | sales@shringchem.com | China | 3545 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| mahaloong | +86-028-81192082 +86-18180560816 | sales@mahaloong.com | China | 94 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | 18051384581 | sales@chemhifuture.com | China | 3063 | 58 |