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2-ethyl-5-nitroaniline

2-ethyl-5-nitroaniline structure

CAS No.: 20191-74-6

Chemical Name:: 2-ethyl-5-nitroaniline

Synonyms: Pazopanib Impurity 53;Pazopanil Impurity 38;2-ethyl-5-nitroaniline;2-ethyl-5-nitrobenzenamine;2-Ethyl-5-nitro-phenylaMine;BenzenaMine, 2-ethyl-5-nitro-;4-Nitro-2-amino-1-ethylbenzene;2-Ethyl-5-nitrobenzenamine 98%;2-Ethyl-5-nitrobenzenamine ,98%;2-Ethyl-5-nitroaniline 2-Ethyl-5-nitrobenzenamine

CBNumber:: CB12129191

Molecular Formula:: C8H10N2O2

Molecular Weight:: 166.18

MDL Number:: MFCD00034056

MOL File:: 20191-74-6.mol

MSDS File:: SDS

Last updated:2026-01-13 11:11:21

Product description	Number	Pack Size	Price
2-ETHYL-5-NITROANILINE Aldrich^CPR	S752118	1 unit	$197
2-ETHYL-5-NITROANILINE Aldrich	S752118	100mg	$179
2-Ethyl-5-nitroaniline >98.0%(GC)	E1085	1g	$108
2-Ethyl-5-nitroaniline >98.0%(GC)	E1085	5g	$384
2-Ethyl-5-nitrobenzenamine	E925233	1g	$75
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2-ethyl-5-nitroaniline Properties

Melting point	63-64℃ (methanol )
Boiling point	335.3±22.0 °C(Predicted)
Density	1.218±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	powder to crystal
pka	2.25±0.10(Predicted)
color	Light yellow to Brown
InChI	InChI=1S/C8H10N2O2/c1-2-6-3-4-7(10(11)12)5-8(6)9/h3-5H,2,9H2,1H3
InChIKey	MMZWMCKTKJKIMC-UHFFFAOYSA-N
SMILES	C1(N)=CC([N+]([O-])=O)=CC=C1CC
CAS DataBase Reference	20191-74-6

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H332-H302-H312

Precautionary statements

P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501

Risk Statements

20/21/22

Safety Statements

36/37

HS Code

29214200

NFPA 704

	0
2		0

2-ethyl-5-nitroaniline price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S752118	2-ETHYL-5-NITROANILINE Aldrich^CPR	20191-74-6	1 unit	$197	2026-04-30	Buy
Sigma-Aldrich	S752118	2-ETHYL-5-NITROANILINE Aldrich	20191-74-6	100mg	$179	2024-03-01	Buy
TCI Chemical	E1085	2-Ethyl-5-nitroaniline >98.0%(GC)	20191-74-6	1g	$108	2026-04-30	Buy
TCI Chemical	E1085	2-Ethyl-5-nitroaniline >98.0%(GC)	20191-74-6	5g	$384	2026-04-30	Buy
TRC	E925233	2-Ethyl-5-nitrobenzenamine	20191-74-6	1g	$75	2021-12-16	Buy

Product number	Packaging	Price	Buy
S752118	1 unit	$197	Buy
S752118	100mg	$179	Buy
E1085	1g	$108	Buy
E1085	5g	$384	Buy
E925233	1g	$75	Buy

2-ethyl-5-nitroaniline Chemical Properties,Uses,Production

Chemical Properties

Yellow to light brown or brown solid

Synthesis

578-54-1

20191-74-6

General procedure for the synthesis of 2-ethyl-5-nitroaniline from 2-ethylaniline: 2-ethylaniline (24.2 g, 0.2 mol) was slowly added to concentrated sulfuric acid (100 mL), keeping the temperature of the reaction system lower than 0°C. The reaction was carried out at a controlled temperature. Fuming nitric acid (18.6 g, 0.3 mol) was slowly added dropwise under strictly controlled temperature conditions. After the dropwise addition, the reaction mixture was kept stirring at room temperature. Upon completion of the reaction, the reaction solution was carefully poured into ice water (1000 mL) and stirred while adding. Subsequently, the pH of the mixture was adjusted slowly by adding 50% sodium hydroxide solution to about 8. The precipitate was collected by filtration and the filter cake was recrystallized with petroleum ether to give 2-ethyl-5-nitroaniline (26.6 g, 80.1% yield) as a yellow needle-like solid.

References

[1] Patent: CN103373989, 2016, B. Location in patent: Paragraph 0031; 0032
[2] Patent: CN103739550, 2016, B. Location in patent: Paragraph 0125-0129
[3] Tetrahedron, 1990, vol. 46, # 17, p. 6085 - 6112
[4] Journal of Medicinal Chemistry, 2008, vol. 51, # 15, p. 4632 - 4640
[5] Patent: WO2009/62658, 2009, A1. Location in patent: Page/Page column 33; 1/10

2-ethyl-5-nitroaniline Preparation Products And Raw materials

Raw materials

2-Ethylaniline 1-ethyl-2,4-dinitrobenzene

Preparation Products

3-Methyl-6-nitroindazole 3-methyl-1H-indazol-6-amine 3-Chloro-4-ethylaniline

2-ethyl-5-nitroaniline Suppliers

Global( 141)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1319	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
GLR Innovations	+91 9891111994	info@glrgroup.in	India	4535	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Shanghai Yingrui Biopharma Co.,Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
GLR Innovations	58

View Lastest Price from 2-ethyl-5-nitroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-17	2-Ethyl-5-nitroaniline 20191-74-6	US $3.00-9.00 / KG	0.1KG	99%	g-kg-tons, free sample is available	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2024-10-31	2-Ethyl-5-nitrobenzenamine 20191-74-6	US $0.00 / g	10g	98%	10tons	Yangzhou Qinyuan Pharmatech Co.,ltd
2019-07-06	Benzenamine,2-ethyl-5-nitro- 20191-74-6	US $2.00 / KG	1KG	99%	20ton	Career Henan Chemical Co

2-Ethyl-5-nitroaniline
20191-74-6
US $3.00-9.00 / KG
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2-Ethyl-5-nitrobenzenamine
20191-74-6
US $0.00 / g
98%
Yangzhou Qinyuan Pharmatech Co.,ltd

Benzenamine,2-ethyl-5-nitro-
20191-74-6
US $2.00 / KG
99%
Career Henan Chemical Co

2-ethyl-5-nitroaniline Spectrum

2-ethyl-5-nitroaniline(20191-74-6)¹HNMR

20191-74-6(2-ethyl-5-nitroaniline)Related Search:

3-Methyl-6-nitroindazole 5-Amino-2-methylbenzenesulfonamide N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine Pazopanib Impurity 48 3-methyl-1H-indazol-6-amine

5-Amino-2,3-dimethyl-2H-indazole Pazopanib Impurity 32 2,4-Dichloropyrimidine Benzenamine, 2-ethyl-4-nitro- 3-AMINO-4-METHYLBENZENESULFONAMIDE

2-amino-5-methylbenzenesulfonamide Pazopanib-d6 2H-Indazol-4-amine, 2,3-dimethyl- 1H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-3-methyl- 6-Nitroindazole

Pazopanib Impurity 47 1,1,3,3,5-PENTAMETHYL-4,6-DINITROINDANE METHYL 2,4-DINITROPHENYLACETATE

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2-Ethyl-5-nitrobenzenamine ,98% 2-ethyl-5-nitroaniline BenzenaMine, 2-ethyl-5-nitro- 2-Ethyl-5-nitro-phenylaMine 4-Nitro-2-amino-1-ethylbenzene 2-Ethyl-5-nitroaniline 2-Ethyl-5-nitrobenzenamine 2-Ethyl-5-nitrobenzenamine 98% Pazopanib Impurity 53 2-ethyl-5-nitroanilineQ: What is 2-ethyl-5-nitroaniline Q: What is the CAS Number of 2-ethyl-5-nitroaniline Q: What is the storage condition of 2-ethyl-5-nitroaniline 2-ethyl-5-nitrobenzenamine Pazopanil Impurity 38 20191-74-6 0191-74-6