2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
- CAS No.
- 503176-50-9
- Chemical Name:
- 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
- Synonyms
- 3-Fluoro-4-formylphenylboronic acid pinacol ester;3-Fluoro-4-forMylbenzeneboronic acid pinacol ester, 96%;2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde;2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane-2-yl)Benzaldehyde;Benzaldehyde, 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- CBNumber:
- CB12513268
- Molecular Formula:
- C13H16BFO3
- Molecular Weight:
- 250.07
- MDL Number:
- MFCD16036135
- MOL File:
- 503176-50-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Fluoro-4-formylphenylboronicacidpinacolester | F591670 | 100mg | $45 |
| 3-Fluoro-4-formylphenylboronicacidpinacolester | F591670 | 250mg | $50 |
| 2-FLUORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZALDEHYDE 95.00% | BOR0006404 | 5MG | $500.1 |
| 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 95+% | 097402 | 5g | $588 |
| 3-Fluoro-4-formylphenylboronicacidpinacolester | X0870 | 1g | $100 |
| More product size | |||
| storage temp. | Inert atmosphere,2-8°C |
|---|---|
| form | Solid |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 503176-50-9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | F591670 | 3-Fluoro-4-formylphenylboronicacidpinacolester | 503176-50-9 | 100mg | $45 | 2021-12-16 | Buy |
| TRC | F591670 | 3-Fluoro-4-formylphenylboronicacidpinacolester | 503176-50-9 | 250mg | $50 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BOR0006404 | 2-FLUORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZALDEHYDE 95.00% | 503176-50-9 | 5MG | $500.1 | 2021-12-16 | Buy |
| Matrix Scientific | 097402 | 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 95+% | 503176-50-9 | 5g | $588 | 2021-12-16 | Buy |
| AK Scientific | X0870 | 3-Fluoro-4-formylphenylboronicacidpinacolester | 503176-50-9 | 1g | $100 | 2021-12-16 | Buy |
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde Chemical Properties,Uses,Production
Synthesis
57848-46-1
73183-34-3
503176-50-9
In a pressure tube reactor, 4-bromo-2-fluorobenzaldehyde (500 mg, 2.46 mmol), 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bis(1,3,2-dioxaborolane) (938 mg, 3.69 mmol), Pd(dppf)2Cl2 (120 mg, 0.15 mmol), dppf (78 mg, 0.15 mmol) and KOAc (965 mg, 9.84 mmol) were added sequentially. Subsequently, 1,4-dioxane (8 mL) was added as solvent and the reaction was stirred at 85 °C for 13 h under nitrogen protection. Upon completion of the reaction, the reaction mixture was extracted several times with ethyl acetate and water, and the organic layers were combined and dried over anhydrous sodium sulfate to remove water. After concentration under reduced pressure, the product was purified by column chromatography (eluent: 20% ethyl acetate/hexane) to afford the target product 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde in 96% yield. The product was characterized by 1H-NMR (300 MHz, CDCl3): δ 10.38 (s, 1H), 7.85-7.81 (m, 1H), 7.67-7.65 (m, 1H), 7.57 (s, J = 10.4 Hz, 1H), 1.35 (s, 12H).
References
[1] Patent: US2015/259350, 2015, A1. Location in patent: Paragraph 0181; 0182
[2] Patent: KR101745741, 2017, B1. Location in patent: Paragraph 0285
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | sales@hengbeichem.cn | China | 6854 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
| Shanghai Scochem Technology Co., Ltd | +86-021-33758897 +86-13701882790 | sales@scochem.com | China | 1977 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30123 | 84 |
| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44802 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14101 | 59 |
| Supplier | Advantage |
|---|---|
| Alchem Pharmtech,Inc. | 58 |
| career henan chemical co | 58 |
| Nanjing Hengbei Chemicals Co., Ltd. | 58 |
| Aromsyn Co., Ltd. | 58 |
| Shanghai Scochem Technology Co., Ltd | 58 |
| Aladdin Scientific | 58 |
| Amadis Chemical Company Limited | 58 |
| Alfa Aesar | 84 |
| Energy Chemical | 61 |
| Adamas Reagent, Ltd. | 59 |
View Lastest Price from 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-04 | 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
503176-50-9
|
US $0.01 / KG | 1KG | 98%; 99% | 1kg; 5kg | Career Henan Chemical Co |
-
- 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
503176-50-9
- US $0.01 / KG
- 98%; 99%
- Career Henan Chemical Co
503176-50-9(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde)Related Search:
1of2
