Magnesium Orotate
- CAS No.
- 34717-03-8
- Chemical Name:
- Magnesium Orotate
- Synonyms
- TUBB3;CDCBM;TUBB4;CFEOM3A;beta-4)-;Tubulin β-4;Tubulin β-III;tubulin, beta 3;Tubulin β-3 chain;MAGNESIUM OROTATE
- CBNumber:
- CB1257706
- Molecular Formula:
- C10H4MgN4O8
- Molecular Weight:
- 332.47
- MDL Number:
- MFCD00039120
- MOL File:
- 34717-03-8.mol
| storage temp. | -20°C |
|---|---|
| InChI | InChI=1S/2C5H4N2O4.Mg/c2*8-3-1-2(4(9)10)6-5(11)7-3;/h2*1H,(H3,6,7,8,9,10,11);/q;;+4/p-4 |
| InChIKey | MEZKYWVZYGZEHX-UHFFFAOYSA-J |
| SMILES | O=C1NC(=O)C=C2C(=O)[O-][Mg+2]3([O-]C(=O)C4=CC(=O)NC(=O)N34)N12 |
| LogP | -0.928 (est) |
| FDA UNII | GI96W46M5A |
| ATC code | A12CC09 |
| EPA Substance Registry System | Magnesium, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-.kappa.N3,.kappa.O4)-, (T-4)- (34717-03-8) |
Magnesium Orotate price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 142656 | Tubulin Beta 3 | 34717-03-8 | 200ul | $446 | 2021-12-16 | Buy |
| Usbiological | T9155-11 | Tubulin, beta 3 | 34717-03-8 | 200ug | $736 | 2021-12-16 | Buy |
| Matrix Scientific | 059672 | Magnesium bis(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate) | 34717-03-8 | 500mg | $199 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb528408 | TUBB3 | 34717-03-8 | 10μg | $290.7 | 2021-12-16 | Buy |
| AK Scientific | X4062 | Magnesiumorotate | 34717-03-8 | 500mg | $318 | 2021-12-16 | Buy |
Magnesium Orotate Chemical Properties,Uses,Production
Description
Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of pyrimidines that promotes the synthesis of enzymes which act as free radical scavengers. Experiments investigating the potential cardioprotective actions of orotic acid in pathological heart conditions are still ongoing.
Uses
magnesium orotate is used as an adjuvant treatment in congestive heart failure, hyperten-sion, post-operative cardiac status or in type 2 diabetes.
Magnesium orotate combines in itself the cardio protective properties of magnesium and orotic acid and leads to the optimisation of the magnesium effect by reducing cellular magnesium loss.
At the same time, animal studies have indicated a protective effect of magnesium orotate with respect to atherosclerotic vascular changes. The efficacy of the combination was superior to the effect of the individual components of magnesium and orotic acid.
Preparation
For the synthesis of magnesium orotate and due to the low solubility of both magnesium hydroxide and orotic acid, 50 mL H2O were heated up to 70 °C. Half of the magnesium hydroxide (total: 0.125 g, 2.16 mmol, 1 eq.) was added to the warm solution. Subsequently, small amounts of both orotic acid (total: 0.75 g, 4.31 mmol, 2 eq.) and the remaining magnesium hydroxide were added alternatingly. After heating the solution to 90 °C and stirring it for 30 min, it was stored in the fridge for crystallization. After one weekend, 0.70 g (1.46 mmol, 68 %) of a white microcrystalline material could be obtained after filtration and drying.
IR, NMR and PXRD analysis (presented in sections S2 and S4) confirmed the product to be magnesium orotate octahydrate.
Magnesium Orotate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Baishixing Science and Technology Industry Co.,Ltd | +86-15008457246 +86-15008457246 | yuki@cd-bsx.com | China | 53 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 2259 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
View Lastest Price from Magnesium Orotate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-19 | Magnesium oratate
34717-03-8
|
US $15.00 / kg | 1kg | 99.912% | 10ton | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2023-10-10 | Magnesium Orotate
34717-03-8
|
US $4.75 / KG | 1KG | 99% | 15MT | Wuhan Han Sheng New Material Technology Co.，Ltd | |
 |
2023-10-09 | beta-4
34717-03-8
|
US $4.71 / KG | 1KG | 99% | 15MT | Wuhan Han Sheng New Material Technology Co.，Ltd |
-
- Magnesium oratate
34717-03-8
- US $15.00 / kg
- 99.912%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Magnesium Orotate
34717-03-8
- US $4.75 / KG
- 99%
- Wuhan Han Sheng New Material Technology Co.，Ltd
-
- beta-4
34717-03-8
- US $4.71 / KG
- 99%
- Wuhan Han Sheng New Material Technology Co.，Ltd