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FTI-277

CAS No.
170006-73-2
Chemical Name:
FTI-277
Synonyms
FTI-277;FTI-277;FTI277;METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA;N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester;N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
CBNumber:
CB1266050
Molecular Formula:
C22H29N3O3S2
Molecular Weight:
447.61
MDL Number:
MFCD00952925
MOL File:
170006-73-2.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:12

FTI-277 Properties

Boiling point 684.2±55.0 °C(Predicted)
Density 1.222±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: soluble
pka 9.81±0.10(Predicted)
form amorphous semi-solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

FTI-277 price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F9803 FTI-277 trifluoroacetate salt ≥95% (HPLC), amorphous semi-solid 170006-73-2 1mg $190 2024-03-01 Buy
Sigma-Aldrich F9803 FTI-277 trifluoroacetate salt ≥95% (HPLC), amorphous semi-solid 170006-73-2 5mg $697 2024-03-01 Buy
Tocris 2407 FTI277 ≥95%(HPLC) 170006-73-2 1 $148 2021-12-16 Buy
Usbiological 255341 FTI 277 170006-73-2 1mg $389 2021-12-16 Buy
American Custom Chemicals Corporation INB0003962 FTI-277 95.00% 170006-73-2 5MG $501.88 2021-12-16 Buy
Product number Packaging Price Buy
F9803 1mg $190 Buy
F9803 5mg $697 Buy
2407 1 $148 Buy
255341 1mg $389 Buy
INB0003962 5MG $501.88 Buy

FTI-277 Chemical Properties,Uses,Production

Uses

Farnesyltransferase inhibitor 277 (FTI-277) has been used to:

  • inhibit protein farnesylation in breast cell lines.
  • in marrow-isolated adult multilineage inducible cells (MIAMI).
  • inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).

Biochem/physiol Actions

Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.

FTI-277 Preparation Products And Raw materials

Raw materials

Preparation Products

FTI-277 Suppliers

Global( 58)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2784 58

View Lastest Price from FTI-277 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FTI-277 trifluoroacetate salt pictures 2020-01-10 FTI-277 trifluoroacetate salt
170006-73-2
US $1.00 / g 1g 99% 200kg Career Henan Chemical Co
METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA FTI-277 N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester FTI-277;FTI277 L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester 170006-73-2 C22H29N3O3S2 C22H29N3O3S2C2HF3O2