DisodiuM trans-crocetinate
- CAS No.
- 591230-99-8
- Chemical Name:
- DisodiuM trans-crocetinate
- Synonyms
- Crocetin disodium;Transcrocetinate sodium;Transcrocetinate disodium;DisodiuM trans-crocetinate;Disodium salt of saffron acid;Trans Sodium Crocetinate( Disodium trans-crocetinate);Transcrocetinate disodium (Disodium trans-crocetinate);Transcrocetinate disodium (Synonyms: Disodium trans-crocetinate);iGluR,Transcrocetinate disodium,Inhibitor,inhibit,Ionotropic glutamate receptors
- CBNumber:
- CB12668641
- Molecular Formula:
- C20H25NaO4
- Molecular Weight:
- 352.41
- MDL Number:
- MOL File:
- 591230-99-8.mol
| storage temp. | Store at -20°C |
|---|---|
| solubility | H2O:16.67(Max Conc. mg/mL);44.77(Max Conc. mM) |
| FDA UNII | YP57637WMX |
DisodiuM trans-crocetinate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0006368 | Transcrocetinatedisodium | 591230-99-8 | 100mg | $750 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb572893 | Transcrocetinate disodium | 591230-99-8 | 100mg | $838.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb572893 | Transcrocetinate disodium | 591230-99-8 | 250mg | $1654.1 | 2021-12-16 | Buy |
| DC Chemicals | DC12170 | Transcrocetinatedisodium(Disodiumtrans-crocetinate) >98% | 591230-99-8 | 1g | $2200 | 2021-12-16 | Buy |
| DC Chemicals | DC12170 | Transcrocetinatedisodium(Disodiumtrans-crocetinate) >98% | 591230-99-8 | 250mg | $1100 | 2021-12-16 | Buy |
DisodiuM trans-crocetinate Chemical Properties,Uses,Production
Biological Activity
DisodiuM trans-crocetinate, extracted from saffron (Crocus sativus L.), is a high-affinity NMDA receptor antagonist.
in vitro
Transcrocetinate (Transcrocetin, trans-Crocetin), a saffron metabolite originating from the crocin apocarotenoids, has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron. To ensure unchanged viability of Caco-2 cells throughout the transport experiments, cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 μM) reveal no negative significant changes in cellular viability. Transcrocetinate at 10 μM level does not change viability while higher concentrations (40-160 μM) reduces significantly cellular viability.
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target
NMDA receptor
DisodiuM trans-crocetinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
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