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ARS-1620

ARS-1620 structure

CAS No.: 1698055-85-4

Chemical Name:: ARS-1620

Synonyms: CPD1588;ARS-1620;ARS-1620;ARS 1620;ARS1620;inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620;(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;(S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one;2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-;1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one

CBNumber:: CB13369787

Molecular Formula:: C21H17ClF2N4O2

Molecular Weight:: 430.84

MDL Number:: MFCD31619312

MOL File:: 1698055-85-4.mol

Last updated:2023-05-21 10:59:17

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ARS-1620 Properties

Boiling point	614.7±55.0 °C(Predicted)
Density	1.434±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:70.0(Max Conc. mg/mL);162.47(Max Conc. mM)
form	A solid
pka	6.03±0.35(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338

ARS-1620 price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	27915	ARS1620	1698055-85-4	1mg	$118	2024-03-01	Buy
Cayman Chemical	27915	ARS1620	1698055-85-4	5mg	$351	2024-03-01	Buy
ChemScene	CS-0035119	ARS-1620 99.20%	1698055-85-4	25mg	$690	2021-12-16	Buy
ChemScene	CS-0035119	ARS-1620 99.20%	1698055-85-4	50mg	$990	2021-12-16	Buy
ChemScene	CS-0035119	ARS-1620 99.20%	1698055-85-4	100mg	$1250	2021-12-16	Buy

Product number	Packaging	Price	Buy
27915	1mg	$118	Buy
27915	5mg	$351	Buy
CS-0035119	25mg	$690	Buy
CS-0035119	50mg	$990	Buy
CS-0035119	100mg	$1250	Buy

ARS-1620 Chemical Properties,Uses,Production

Uses

ARS-1620, is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.

Definition

ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.

ARS-1620 Preparation Products And Raw materials

Raw materials

Preparation Products

ARS-1620 Suppliers

Global( 77)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
career henan chemical co	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
ANHUI WITOP BIOTECH CO., LTD	58
Finetech Industry Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
TargetMol Chemicals Inc.	58

View Lastest Price from ARS-1620 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-19	ARS-1620 1698055-85-4	US $1.00 / KG	1KG	99.0%	100kg	Career Henan Chemical Co

ARS-1620
1698055-85-4
US $1.00 / KG
99.0%
Career Henan Chemical Co

1698055-85-4(ARS-1620)Related Search:

Sotorasib CPI-444 Bardoxolone methyl

ARS-1620 CPD1588 ARS-1620;ARS 1620;ARS1620 (S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one 1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one 2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]- (S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620 1698055-85-4 C21H17ClF2N4O2 APIs API