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2,5-OXAZOLIDINEDIONE

CAS No.
2185-00-4
Chemical Name:
2,5-OXAZOLIDINEDIONE
Synonyms
GLY-NCA;L-Gly-NCA;2,5-OXAZOLIDINEDIONE;oxazolidine-2,5-dione;2,5-Oxazolidinedione 98%;1,3-oxazolidine-2,5-dione;GLYCINE-N-CARBOXYANHYDRIDE;N-Carboxyglycine anhydride
CBNumber:
CB1432288
Molecular Formula:
C3H3NO3
Molecular Weight:
101.06
MDL Number:
MFCD00075543
MOL File:
2185-00-4.mol
Last updated:2024-01-17 16:57:51

2,5-OXAZOLIDINEDIONE Properties

Melting point 120 °C (dec.) (lit.)
Density 1.469±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 9.32±0.20(Predicted)
CAS DataBase Reference 2185-00-4
FDA UNII 9V6987Y758

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318-H315-H335
Precautionary statements  P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
WGK Germany  3

2,5-OXAZOLIDINEDIONE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 369772 2,5-Oxazolidinedione 98% 2185-00-4 1g $208 2024-03-01 Buy
Sigma-Aldrich 369772 2,5-Oxazolidinedione 98% 2185-00-4 5g $713 2024-03-01 Buy
Matrix Scientific 094908 Oxazolidine-2,5-dione 95+% 2185-00-4 10g $977 2021-12-16 Buy
Matrix Scientific 094908 Oxazolidine-2,5-dione 95+% 2185-00-4 1g $227 2021-12-16 Buy
AK Scientific 1066AB Oxazolidine-2,5-dione 2185-00-4 1g $172 2021-12-16 Buy
Product number Packaging Price Buy
369772 1g $208 Buy
369772 5g $713 Buy
094908 10g $977 Buy
094908 1g $227 Buy
1066AB 1g $172 Buy

2,5-OXAZOLIDINEDIONE Chemical Properties,Uses,Production

Preparation

Phosgene was passed in a fine stream into a suspension of finely ground glycine (15 g) in dry dioxane (750 mL) at 45–50 ℃ with efficient agitation. A clear solution was obtained after 5 h. This solution was filtered to remove unreacted glycine (1.7 g), and the dioxane was then removed under reduced pressure at a temperature below 40 ℃ under exclusion of moisture. The residue was treated with dry diethyl ether (100 mL), and the crystals of 2,5-oxazolidinedione were collected by filtration and dried over P2O5 in a vacuum desiccator. The crude product thus obtained, 16 g (89%), was recrystallized from ethyl acetate/petroleum ether to yield 14.3 g (77.2%) of pure material, which showed no melting point because of polymerization.

Preparation

Into a suspension of finely ground glycine (15 g) in dry dioxane (750 mL), phosgene was introduced in a fine stream at 45–50 °C with efficient agitation. A clear solution was obtained after 5 h. This solution was filtered to remove unreacted glycine (1.7 g), and the dioxane was then removed under reduced pressure at a temperature below 40 °C with protection from moisture. The residue was treated with dry diethyl ether (100 mL), and the crystals of 2,5-oxazolidinedione were collected by filtration and dried over P2O5 in a vacuum desiccator. The crude product so obtained, 16 g (89%), was recrystallized from ethyl acetate/petroleum ether to yield 14.3 g (77.2%) of pure material, which showed no melting point because of polymerization.

67-66-3
56-40-6
2185-00-4
Synthesis of 2,5-OXAZOLIDINEDIONE from Chloroform and Glycine
Global( 90)Suppliers
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Sichuan HongRi Pharma-Tech Co.,Ltd
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Aladdin Scientific
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View Lastest Price from 2,5-OXAZOLIDINEDIONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Gly-NCA pictures 2024-04-26 Gly-NCA
2185-00-4
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
2,5-OXAZOLIDINEDIONE pictures 2020-01-09 2,5-OXAZOLIDINEDIONE
2185-00-4
US $6.68 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
  • Gly-NCA pictures
  • Gly-NCA
    2185-00-4
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
N-Carboxyglycine anhydride GLY-NCA GLYCINE-N-CARBOXYANHYDRIDE oxazolidine-2,5-dione L-Gly-NCA 2,5-OXAZOLIDINEDIONE 1,3-oxazolidine-2,5-dione 2,5-Oxazolidinedione 98% 2185-00-4 pharmacetical Anhydride Monomers Monomers Polymer Science