Membrane Scaffold Protein 1D1 Delta-Helix 5
- CAS No.
- Chemical Name:
- Membrane Scaffold Protein 1D1 Delta-Helix 5
- Synonyms
- Membrane Scaffold Protein 1D1 Delta-Helix 5
- CBNumber:
- CB14670143
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Membrane Scaffold Protein 1D1 Delta-Helix 5 price More Price(1)
Membrane Scaffold Protein 1D1 Delta-Helix 5 Chemical Properties,Uses,Production
Uses
For guidelines on the use of this and other MSP′s to prepare Nanodiscs, please visit our Protocols for Membrane Scaffold Proteins and Nanodisc Formation page.
General Description
Nanodisc technology is an approach to render membrane proteins soluble in aqueous solutions in a native-like bilayer environment, where the membrane proteins remain stable and active. The Nanodisc concept is derived from high density lipoprotein (HDL) particles and their primary protein component, apolipoprotein. The Nanodisc is a non-covalent structure of phospholipid bilayer and membrane scaffold protein (MSP), a genetically engineered protein, which mimics the function of Apolipoprotein A-1 (ApoA-1).
The first MSP, MSP1, was engineered with its sequence based on the sequence of A-1, but without the globular N-terminal domain of native A-1. The Membrane Scaffold Protein 1D1 (MSP1D1) variant of MSP1 deletes the first 11 amino acids in the Helix 1 portion (referred to as “H0.5” in the accompanying figure) of the original MSP1 sequence. The MSP1D1ΔH5 variant of MSP1D1 omits the 22 amino acids of the Delta-Helix 5 sequence (H5).
Membrane Scaffold Protein 1D1 Delta-Helix 5 Preparation Products And Raw materials
Raw materials
Preparation Products
Membrane Scaffold Protein 1D1 Delta-Helix 5 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |