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ChemicalBook >> CAS DataBase List >>8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Structure
8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol structure
CAS No.
117811-17-3
Chemical Name:
8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol
Synonyms
Desloratadine Dehydro 11-Hydroxy N-Methyl Impurity;8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol;8-chloro-11-(1-methylpiperidin-4-yl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol;11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-11-(1-methyl-4-piperidinyl)-
CBNumber:
CB15992741
Molecular Formula:
C20H21ClN2O
Molecular Weight:
340.85
MDL Number:
MOL File:
117811-17-3.mol
Last updated:2023-05-15 10:44:02
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8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Properties

Boiling point 509.8±50.0 °C(Predicted)
Density 1.267±0.06 g/cm3(Predicted)
solubility soluble in Dichloromethane
pka 11.94±0.20(Predicted)
form Solid
color Yellow

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Chemical Properties,Uses,Production

Uses

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is an intermediate in synthesizing Ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate (E902775). It is an impurity of loratadine (L469575), which is a nonsedating-type histamine H1-receptor.

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Preparation Products And Raw materials

Raw materials

Preparation Products

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Suppliers

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Henan Vcommend Consultrading Co., Ltd. 58
8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Desloratadine Dehydro 11-Hydroxy N-Methyl Impurity 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-11-(1-methyl-4-piperidinyl)- 8-chloro-11-(1-methylpiperidin-4-yl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol 117811-17-3