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PYD-106

PYD-106 structure

CAS No.: 1560894-05-4

Chemical Name:: PYD-106

Synonyms: PYD-106;PYD106,PYD 106;4-[3-acetyl-2,5-dihydro-4-hydroxy-1-[2-(2-methyl-1H-indol-3-yl)ethyl]-5-oxo-1H-pyrrol-2-yl]-benzoic acid, methyl ester

CBNumber:: CB16197693

Molecular Formula:: C25H24N2O5

Molecular Weight:: 432.47

MDL Number:

MOL File:: 1560894-05-4.mol

Last updated:2023-05-21 10:59:17

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PYD-106 Properties

Boiling point	723.0±60.0 °C(Predicted)
Density	1.339±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: soluble
form	A solid
pka	4.50±1.00(Predicted)

PYD-106 Chemical Properties,Uses,Production

Biological Activity

PYD-106 is a positive allosteric modulator of NR2C subunit-containing NMDA receptors (NMDARs).1 It enhances glutamate-induced maximal current responses in HEK293 cells expressing NR1/NR2C NMDA receptors (EC50 = 13 μM). PYD-106 is selective for NR2C subunit-containing NMDA receptors over NRA-, NR2B-, and NR2D-subunit containing NMDA receptors in Xenopus oocytes expressing NR1/NR2 heteromeric NMDA receptors at 30 μM.

References

1.Khatri, A., Burger, P.B., Swanger, S.A., et al.Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulatorMol. Pharmacol.86(5)548-560(2014)

PYD-106 Preparation Products And Raw materials

Raw materials

Preparation Products

PYD-106 Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1249	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	5141	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Shanghai EFE Biological Technology Co., Ltd.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Changzhou Furuisi Biotechnology Co., Ltd	58
Beijing Biocreative Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Nanjing Tengyi Biotechnology Co., Ltd	58

PYD-106 PYD106,PYD 106 4-[3-acetyl-2,5-dihydro-4-hydroxy-1-[2-(2-methyl-1H-indol-3-yl)ethyl]-5-oxo-1H-pyrrol-2-yl]-benzoic acid, methyl ester 1560894-05-4