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ChemicalBook >> CAS DataBase List >>Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Structure
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- structure
CAS No.
2225940-51-0
Chemical Name:
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Synonyms
IUN 40510;Poma-C7-COOH;Pomalidomide-C7-COOH;Thalidomide-NH-C7-COOH;Thalidomide-4-NH-C7-COOH;Pomalidomide 4'-alkylC7-acid;8-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]octanoic Acid;8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanoic acid;8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}octanoic acid;Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
CBNumber:
CB18094244
Molecular Formula:
C21H25N3O6
Molecular Weight:
415.44
MDL Number:
MFCD32857157
MOL File:
2225940-51-0.mol
Last updated:2023-06-30 15:45:59
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Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Chemical Properties,Uses,Production

Biological Activity

Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].

storage

Store at -20°C

References

[1]. Zhang X, et, al. Discovery of PROTAC BCL-X L degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15; 192: 112186.

Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Suppliers

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Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
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Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 6854 65
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Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Daicel Chiral Technologies (China)CO.,LTD 65
Shanghai Chaolan Chemical Technology Center 58
Aikon International Limited 58
Henan Alfachem Co.,Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58

2225940-51-0(Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-)Related Search:

E3 ligase Ligand-Linker Conjugates 49 Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid Pomalidomide-C6-PEG3-butyl iodide POMALIDOMIDE-C9-CO2H
Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 55 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-6-2-2-6-N3
Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

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Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Pomalidomide-C7-COOH 8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}octanoic acid IUN 40510 8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanoic acid Thalidomide-NH-C7-COOH 8-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]octanoic Acid Thalidomide-4-NH-C7-COOH Poma-C7-COOH Pomalidomide 4'-alkylC7-acid 2225940-51-0