Avermectin B1b
- CAS No.
- 65195-56-4
- Chemical Name:
- Avermectin B1b
- Synonyms
- AbaMectin B1b;C-076B1b;avermectin b1b;Antibiotic C-076B1b;Abamectin B1b (~90%);Ivermectin Impurity 2(Ivermectin EP Impurity B);5-O-Demethyl-25-de(1-methylpropyl)-25-isopropylAvermectin A1a;Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-
- CBNumber:
- CB1855054
- Molecular Formula:
- C47H70O14
- Molecular Weight:
- 859.05
- MDL Number:
- MFCD03701301
- MOL File:
- 65195-56-4.mol
Boiling point | 934.6±65.0 °C(Predicted) |
---|---|
Density | 1.25±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
form | solid |
pka | 12.42±0.70(Predicted) |
color | white |
Stability | Unstable in Solution, Very Hygroscopic |
FDA UNII | W8DT67027W |
EPA Substance Registry System | Avermectin B1b (65195-56-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS09,GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H400-H332-H300 | |||||||||
Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P273-P391-P501-P261-P271-P304+P340-P312 | |||||||||
RIDADR | 2588 | |||||||||
HazardClass | 6.1(a) | |||||||||
PackingGroup | II | |||||||||
NFPA 704 |
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Avermectin B1b price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 17453 | Avermectin B1b ≥99% | 65195-56-4 | 500μg | $189 | 2024-03-01 | Buy |
Cayman Chemical | 17453 | Avermectin B1b ≥99% | 65195-56-4 | 2.5mg | $802 | 2024-03-01 | Buy |
Usbiological | A4447-01 | Avermectin B1b | 65195-56-4 | 500ug | $513 | 2021-12-16 | Buy |
TRC | A107010 | AbamectinB1b(~90%) | 65195-56-4 | 5mg | $1225 | 2021-12-16 | Buy |
TRC | A107010 | AbamectinB1b(~90%) | 65195-56-4 | 0.5mg | $150 | 2021-12-16 | Buy |
Avermectin B1b Chemical Properties,Uses,Production
Uses
Avermectin B1b is the minor component (<20%) of a commercially available anthelmintic used to control parasitic nematodes in livestock. Avermectin B1b contains a isopropyl residue in the 25-position. In vitro and in vivo studies have shown this analogue to be active, but less potent than the B1a analogue
Definition
ChEBI: Avermectin B1b is an avermectin.
brand name
(Merck)Avomec [Veterinary] (Merial); Bovitin [Veterinary] (Merial); Doratect [Veterinary] (Merial); Duomectin [Veterinary] (Merial); Duotin [Veterinary] (Merial); Endecto (Merck); Enzec (Merck); Enzek (Merck); Parafoil (Merck); Vertimil (Zectin (Merck).
Biological Activity
avermectin b1 is a mixture of avermectins containing >80% avermectin b1a and <20% avermectin b1b. b1a and b1b have very similar biological and toxicological properties.
in vitro
the avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium. avermectin b1 is a natural fermentation product of this bacterium.
in vivo
avermectin b1 therapy resulted in significant decreases in mean strongyle egg after treatment. all horses given ivermectin or avermectin b1 had zero strongyle egg counts 14 and 28 d after treatment. the oral administration of avermectin b1 appeared to be highly efficacious against intestinal strongyles and onchocera microfilaria [1].
References
[1] mogg td, pollitt cc, willmore jp, thompson h. efficacy of avermectin b1 given orally against equine intestinal strongyles and onchocera microfilaria. aust vet j. 1990;67(11):399-401.
Avermectin B1b Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14335 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29822 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7193 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
Guangzhou Tosun Pharmaceutical Limited | +8618922120635 | sales@toref-standards.com | China | 1000 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20293 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Suzhou ARTK Medchem Co., Ltd. | +8618168183658 | sales1@artkmedchem.com | China | 39010 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40068 | 58 |
View Lastest Price from Avermectin B1b manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-02-14 | avermectin B1b
65195-56-4
|
US $1.00 / KG | 1KG | Min98% HPLC | G/KG/TON | Career Henan Chemical Co |
- avermectin B1b
65195-56-4
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co
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