ChemicalBook >> CAS DataBase List >>NTRC 00660
NTRC 00660
- CAS No.
- 1817791-73-3
- Chemical Name:
- NTRC 00660
- Synonyms
- NTRC 00660;NTRC 0066 0,NTRC 00660;Pyrimido[4,5-e]indolizine-7-carboxamide, N-(2,6-diethylphenyl)-5,6-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-
- CBNumber:
- CB19631183
- Molecular Formula:
- C33H39N7O2
- Molecular Weight:
- 565.71
- MDL Number:
- MFCD30533281
- MOL File:
- 1817791-73-3.mol
Last updated:2023-03-31 09:12:58
NTRC 00660 Chemical Properties,Uses,Production
Description
NTRC-0066-0 is a a highly potent and selective small molecule inhibitor of TTK. In cell lines and in mice, NTRC 0066-0 inhibits the phosphorylation of a TTK substrate and induces chromosome missegregation. NTRC 0066-0 inhibits tumor growth in MDA-MB-231 xenografts as a single agent after oral application. The combination of NTRC 0066-0 with a therapeutic dose of docetaxel resulted in doubling of mouse survival and extended tumor remission, without toxicity.
NTRC 00660 Preparation Products And Raw materials
Raw materials
Preparation Products
NTRC 00660 Suppliers
Global( 6)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd. | 025-025-58280381 15720605021 | zhang_lei@jsnchem.com | China | 1506 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2380 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24024 | 58 |
| PharmaBlock Sciences (Nanjing), Inc. | 4000255188 | sun_dan@PharmaBlock.com | China | 7268 | 58 |
NTRC 00660
NTRC 0066 0,NTRC 00660
Pyrimido[4,5-e]indolizine-7-carboxamide, N-(2,6-diethylphenyl)-5,6-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-
1817791-73-3