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Deslorelin acetate

CAS No.
82318-06-7
Chemical Name:
Deslorelin acetate
Synonyms
H 4065 Acetate;SoMagard Aceta;PTL 3001 Acetate;BacheM 9022 Acetate;D-Trp LHRH-PEA Acetate;Deslorelin Acetate(acetate);D-Trp6-Pro9-N-ethylaMide-LH-RH Acetate;6-D-Tryptophan-9-(N-ethyl-L-prolinaMide)-1-9-luteinizing HorMone-releasing Factor (Swine) Monoacetate
CBNumber:
CB21105098
Molecular Formula:
C66H87N17O14
Molecular Weight:
1342.50248
MDL Number:
MFCD09842868
MOL File:
82318-06-7.mol
Last updated:2023-11-16 17:50:09

Deslorelin acetate Properties

FDA UNII 679007NR5C

Deslorelin acetate price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FD21216 Deslorelin 82318-06-7 50mg $65 2021-12-16 Buy
Biosynth Carbosynth FD21216 Deslorelin 82318-06-7 100mg $100 2021-12-16 Buy
Biosynth Carbosynth FD21216 Deslorelin 82318-06-7 250mg $200 2021-12-16 Buy
Biosynth Carbosynth FD21216 Deslorelin 82318-06-7 500mg $320 2021-12-16 Buy
Biosynth Carbosynth FD21216 Deslorelin 82318-06-7 1g $510 2021-12-16 Buy
Product number Packaging Price Buy
FD21216 50mg $65 Buy
FD21216 100mg $100 Buy
FD21216 250mg $200 Buy
FD21216 500mg $320 Buy
FD21216 1g $510 Buy

Deslorelin acetate Chemical Properties,Uses,Production

Description

Deslorelin Acetate is a synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production.

Uses

Deslorelin acetate is an injectable gonadotropin-releasing hormone (GnRH) super-agonist (also known as an LHRH agonist), used in treatment of precocious puberty and commonly used in veterinary medicine to induce ovulation in mares.

Preparation

Deslorelin acetate is synthesized from the corresponding protected amino acid monomers by solid or liquid phase synthesis.

References

[1] C L ACKERMANN. Ovarian activity reversibility after the use of deslorelin acetate as a short-term contraceptive in domestic queens.[J]. Theriogenology, 2012, 78 4: 817-822. DOI:10.1016/j.theriogenology.2012.03.030.
[2] R. NOVOTNY . Reversible suppression of sexual activity in tomcats with deslorelin implant[J]. Theriogenology, 2012, 78 4: Pages 848-857. DOI:10.1016/j.theriogenology.2012.03.035.
[3] Y CETIN. Long-term effect of deslorelin implant on ovarian pre-antral follicles and uterine histology in female rats.[J]. Reproduction in Domestic Animals, 2013, 48 2: 195-199. DOI:10.1111/j.1439-0531.2012.02128.x.
[4] BR?NDLI SP. Long-term effect of repeated deslorelin acetate treatment in bitches for reproduction control.[J]. Theriogenology, 2021: 73-82. DOI:10.1016/j.theriogenology.2021.07.015.

Deslorelin acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 33)Suppliers
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Nantong Guangyuan Chemicl Co,Ltd
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View Lastest Price from Deslorelin acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Deslorelin Acetate pictures 2024-03-08 Deslorelin Acetate
82318-06-7
US $10.00 / kg 1kg 99% 1000kg Nantong Guangyuan Chemicl Co,Ltd
6-D-Tryptophan-9-(N-ethyl-L-prolinaMide)-1-9-luteinizing HorMone-releasing Factor (Swine) Monoacetate BacheM 9022 Acetate D-Trp LHRH-PEA Acetate D-Trp6-Pro9-N-ethylaMide-LH-RH Acetate H 4065 Acetate PTL 3001 Acetate SoMagard Aceta Deslorelin Acetate(acetate) 82318-06-7 C66H87N17O14 Amines Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals