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Malabaricone C

CAS No.
63335-25-1
Chemical Name:
Malabaricone C
Synonyms
Malabaricone C;1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-1-nonanone;1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one;1-Nonanone, 1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-;lipid metabolism,Inhibitor,sphingomyelin synthase,SMS 1,diet,obesity,inhibit,Malabaricone C,SMS 2
CBNumber:
CB21120408
Molecular Formula:
C21H26O5
Molecular Weight:
358.43
MDL Number:
MFCD31557586
MOL File:
63335-25-1.mol
MSDS File:
SDS
Last updated:2023-09-20 16:43:00

Malabaricone C Properties

storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
FDA UNII C9K53R3PRN

Malabaricone C price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29741 Malabaricone C 63335-25-1 1mg $37 2024-03-01 Buy
Cayman Chemical 29741 Malabaricone C 63335-25-1 25mg $748 2024-03-01 Buy
Cayman Chemical 29741 Malabaricone C 63335-25-1 5mg $169 2024-03-01 Buy
Cayman Chemical 29741 Malabaricone C 63335-25-1 10mg $319 2024-03-01 Buy
AK Scientific 7286CA MalabariconeC 63335-25-1 1mg $139 2021-12-16 Buy
Product number Packaging Price Buy
29741 1mg $37 Buy
29741 25mg $748 Buy
29741 5mg $169 Buy
29741 10mg $319 Buy
7286CA 1mg $139 Buy

Malabaricone C Chemical Properties,Uses,Production

Description

Malabaricone C is a diarylnonanoid that has been found in Myristica and has diverse biological activities. It scavenges 59.9% of 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals when used at a concentration of 7 μg/ml. Malabaricone C is active against S. aureus, B. subtilis, and C. albicans in vitro (MICs = 2-32 μg/ml). It is cytotoxic to A549, HL-60, and MCF-7 cells (IC50s = 12.3, 46.1, and 10.8 μM, respectively). Malabaricone C inhibits sphingomyelin synthase 1 (SMS1) and SMS2 activity in cell lysates (IC50s = 3 and 1.5 μM, respectively). It decreases body weight gain, hepatic steatosis, and hepatic and plasma triglyceride levels in a mouse model of high-fat diet-induced obesity when administered at a dose of 0.1% in the diet.

Uses

Malabaricone C is a useful research chemical compound from Myristica malabarica which exhibits antioxidant activity.

Definition

ChEBI: A natural product found in Myristica cinnamomea.

699-83-2
63335-25-1
Synthesis of Malabaricone C from 2',6'-Dihydroxyacetophenone

Malabaricone C Preparation Products And Raw materials

Malabaricone C Suppliers

Global( 26)Suppliers
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Jiangsu Yongjian Pharmaceutical Co.,Ltd
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TargetMol Chemicals Inc.
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Chongqing Chemieliva Pharmaceutical Co., Ltd. 023-67770219 jessica.hu@chemieliva.com China 1424 60
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Malabaricone C Spectrum

Malabaricone C 1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one 1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-1-nonanone 1-Nonanone, 1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)- lipid metabolism,Inhibitor,sphingomyelin synthase,SMS 1,diet,obesity,inhibit,Malabaricone C,SMS 2 63335-25-1