5-Chloroindole
- CAS No.
- 17422-32-1
- Chemical Name:
- 5-Chloroindole
- Synonyms
- 5-CHLORO-1H-INDOLE;oroindoL;ChloroIndole;5-CHLOROINDOLE;5-CHLOROINDOLE99%;6-Chloroindole99%;5-Chloroindole 98%;5-Chloroindole >5-Chloroindole ,98%;1H-Indole,5-chloro-
- CBNumber:
- CB2126773
- Molecular Formula:
- C8H6ClN
- Molecular Weight:
- 151.59
- MDL Number:
- MFCD00005672
- MOL File:
- 17422-32-1.mol
- MSDS File:
- SDS
| Melting point | 69-71 °C (lit.) |
|---|---|
| Boiling point | 130 °C / 0.4mmHg |
| Density | 1.1976 (rough estimate) |
| refractive index | 1.5437 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in alcohol. |
| pka | 16.09±0.30(Predicted) |
| form | Crystalline Powder |
| color | White to slightly grayish-green |
| BRN | 2651 |
| InChIKey | MYTGFBZJLDLWQG-UHFFFAOYSA-N |
| CAS DataBase Reference | 17422-32-1(CAS DataBase Reference) |
| FDA UNII | FMJ30GB9J6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 22-24/25-36-26-37/39 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
5-Chloroindole price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C47604 | 5-Chloroindole 98% | 17422-32-1 | 1g | $44.58 | 2024-03-01 | Buy |
| Sigma-Aldrich | C47604 | 5-Chloroindole 98% | 17422-32-1 | 5g | $80.4 | 2024-03-01 | Buy |
| TCI Chemical | C1107 | 5-Chloroindole >98.0%(GC) | 17422-32-1 | 5g | $86 | 2024-03-01 | Buy |
| TCI Chemical | C1107 | 5-Chloroindole >98.0%(GC) | 17422-32-1 | 25g | $254 | 2024-03-01 | Buy |
| Usbiological | 006333 | 5-Chloroindole | 17422-32-1 | 2.5g | $446 | 2021-12-16 | Buy |
5-Chloroindole Chemical Properties,Uses,Production
Chemical Properties
White to slightly greyish-green crystalline powder
Uses
5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts. 5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent
Uses
5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels in the brainstem and telencephalon.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 29, p. 1625, 1992 DOI: 10.1002/jhet.5570290644
The Journal of Organic Chemistry, 44, p. 578, 1979 DOI: 10.1021/jo01318a021
General Description
5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT3 receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.
Purification Methods
It is distilled at high vacuum and recrystallises from pet ether (b 40-60o) or (b 80-100o) as glistening plates. The picrate has m 147o (146.5-147.5o)(from *C6H6). [Rydon & Tweddle J Chem Soc 3499 1955, Sugasawa J Org Chem 44 578 1979, Beilstein 20/4 V 34.]
5-Chloroindole Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7019 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
View Lastest Price from 5-Chloroindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-06 | 5-Chloroindole
17422-32-1
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-09-05 | 5-Chloroindole
17422-32-1
|
US $80.00-55.00 / KG | 1KG | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2022-12-28 | 5-Chloroindole
17422-32-1
|
US $35.00 / kg | 1kg | 99% | 1000kg | Hebei Duling International Trade Co. LTD |
-
- 5-Chloroindole
17422-32-1
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- 5-Chloroindole
17422-32-1
- US $80.00-55.00 / KG
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- 5-Chloroindole
17422-32-1
- US $35.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
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