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Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]-

Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]- structure

CAS No.: 1144075-38-6

Chemical Name:: Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]-

Synonyms: mTOR inhibitor 9d;Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]-

CBNumber:: CB212989997

Molecular Formula:: C21H23N5O3S

Molecular Weight:: 425.5

MDL Number:

MOL File:: 1144075-38-6.mol

Last updated:2025-11-10 14:44:25

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Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]- Properties

Density	1.416±0.06 g/cm3(Predicted)
pka	12.81±0.46(Predicted)

Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]- Chemical Properties,Uses,Production

Uses

mTOR inhibitor-24 (comounp 9d) is a mTOR inhibitor, with IC50s of 0.34 nM (mTOR) and 324 nM (PI3K-α) respectively. mTOR inhibitor-24 inhibtis LNCaP cell proliferation (IC50: 180 nM)[1].

References

[1] Verheijen JC, et al. Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010 Jan 1;20(1):375-9. DOI:10.1016/j.bmcl.2009.10.075

Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]- Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32435	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29641	58
Sangon Biotech (Shanghai) Co.,Ltd.	400-821-026	Sales@sangon.com	China	6710	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
TargetMol Chemicals Inc.	58
Sangon Biotech (Shanghai) Co.,Ltd.	58

View Lastest Price from Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-10	mTOR inhibitor 9d 1144075-38-6	US $147.00-475.00 / mg		99.08%	10g	TargetMol Chemicals Inc.

mTOR inhibitor 9d
1144075-38-6
US $147.00-475.00 / mg
99.08%
TargetMol Chemicals Inc.

Urea, N-(2-hydroxyethyl)-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl]- mTOR inhibitor 9d 1144075-38-6