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Bischloroanthrabenzoxocinone

CAS No.
866022-28-8
Chemical Name:
Bischloroanthrabenzoxocinone
Synonyms
BABX;Bischloroanthrabenzoxocinone;6,16-Epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one, 10,12-dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-, (6R,16R)-
CBNumber:
CB22533948
Molecular Formula:
C28H24Cl2O7
Molecular Weight:
543.392
MDL Number:
MFCD14635432
MOL File:
866022-28-8.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

Bischloroanthrabenzoxocinone Properties

Melting point 167-169 °C(Solv: nitromethane (75-52-5))
Boiling point 660.1±55.0 °C(Predicted)
Density 1.475±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
pka 4.60±0.60(Predicted)

SAFETY

Risk and Safety Statements

HS Code  29419000

Bischloroanthrabenzoxocinone price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19439 Bischloroanthrabenzoxocinone ≥99% 866022-28-8 500μg $340 2024-03-01 Buy
Cayman Chemical 19439 Bischloroanthrabenzoxocinone ≥99% 866022-28-8 2.5mg $1186 2024-03-01 Buy
TRC B418505 Bischloroanthrabenzoxocinone 866022-28-8 1000μg $455 2021-12-16 Buy
Usbiological B2176-23 Bischloroanthrabenzoxocinone 866022-28-8 500ug $523 2021-12-16 Buy
Product number Packaging Price Buy
19439 500μg $340 Buy
19439 2.5mg $1186 Buy
B418505 1000μg $455 Buy
B2176-23 500ug $523 Buy

Bischloroanthrabenzoxocinone Chemical Properties,Uses,Production

Uses

Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 μg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. Type II fatty acid synthesis (FASII) is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). The receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells.

Bischloroanthrabenzoxocinone Preparation Products And Raw materials

Raw materials

Preparation Products

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Bischloroanthrabenzoxocinone BABX 6,16-Epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one, 10,12-dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-, (6R,16R)- 866022-28-8 C28H24Cl2O7 Antibiotic