ChemicalBook >> CAS DataBase List >>Bischloroanthrabenzoxocinone
Bischloroanthrabenzoxocinone
- CAS No.
- 866022-28-8
- Chemical Name:
- Bischloroanthrabenzoxocinone
- Synonyms
- BABX;Bischloroanthrabenzoxocinone;6,16-Epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one, 10,12-dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-, (6R,16R)-
- CBNumber:
- CB22533948
- Molecular Formula:
- C28H24Cl2O7
- Molecular Weight:
- 543.392
- MDL Number:
- MFCD14635432
- MOL File:
- 866022-28-8.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
Bischloroanthrabenzoxocinone price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 19439 | Bischloroanthrabenzoxocinone ≥99% | 866022-28-8 | 500μg | $340 | 2024-03-01 | Buy |
Cayman Chemical | 19439 | Bischloroanthrabenzoxocinone ≥99% | 866022-28-8 | 2.5mg | $1186 | 2024-03-01 | Buy |
TRC | B418505 | Bischloroanthrabenzoxocinone | 866022-28-8 | 1000μg | $455 | 2021-12-16 | Buy |
Usbiological | B2176-23 | Bischloroanthrabenzoxocinone | 866022-28-8 | 500ug | $523 | 2021-12-16 | Buy |
Bischloroanthrabenzoxocinone Chemical Properties,Uses,Production
Uses
Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 μg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. Type II fatty acid synthesis (FASII) is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). The receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells.
Bischloroanthrabenzoxocinone Preparation Products And Raw materials
Raw materials
Preparation Products
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Bischloroanthrabenzoxocinone
BABX
6,16-Epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one, 10,12-dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-, (6R,16R)-
866022-28-8
C28H24Cl2O7
Antibiotic