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ChemicalBook >> CAS DataBase List >>Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester

Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester

Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Structure
Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester structure
CAS No.
1228439-36-8
Chemical Name:
Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester
Synonyms
KCC2 blocker 1;XFXZWVGQXNFWDE-JOCHJYFZSA-N;KCC2 blocker 1,KCC-2 blocker 1;Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester
CBNumber:
CB22667429
Molecular Formula:
C22H25NO5S
Molecular Weight:
415.5026
MDL Number:
MFCD25977014
MOL File:
1228439-36-8.mol
Last updated:2023-05-21 10:59:17
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Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Properties

storage temp. Store at -20°C
solubility DMSO: 250 mg/mL (601.68 mM)

Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0007490 KCC2blocker1 98.60% 1228439-36-8 5mg $600 2021-12-16 Buy
Product number Packaging Price Buy
CS-0007490 5mg $600 Buy

Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Chemical Properties,Uses,Production

Biological Activity

KCC2 blocker 1 is an orally active and selective K+-Cl- cotransporter KCC2 blocker with an IC50 of 1 μM. KCC2 blocker 1 is a benzyl prolinate and has antiepileptic effect[1].

References

[1]. Pégurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5.

Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9180 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
RD International Technology Co., Limited 58
Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester KCC2 blocker 1 XFXZWVGQXNFWDE-JOCHJYFZSA-N KCC2 blocker 1,KCC-2 blocker 1 1228439-36-8