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ChemicalBook >> CAS DataBase List >>Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Structure
Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- structure
CAS No.
1017606-66-4
Chemical Name:
Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
Synonyms
CS-1271;LPA2-IN-1;LPA2 antagonist 1;LPA-2 antagonist 1,LPA2 antagonist 1;N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine;(S)-N-(1-(4-((3,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)propan-2-yl)-7-methylthieno[3,2-d]pyrimidin-4-amine;Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
CBNumber:
CB22668325
Molecular Formula:
C20H23Cl2N5O2S2
Molecular Weight:
500.46
MDL Number:
MFCD28716107
MOL File:
1017606-66-4.mol
Last updated:2025-12-10 09:00:29
Product description Number Pack Size Price
LPA2 Antagonist 1 ≥98% 22051 1mg $236
LPA2 Antagonist 1 ≥98% 22051 5mg $395
LPA2 Antagonist 1 ≥98% 22051 10mg $656
N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine N926243 5mg $350
LPA2antagonist1 99.12% CS-3103 5mg $420
Request For Quotation

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Properties

Boiling point 684.6±65.0 °C(Predicted)
Density 1.453±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
form Powder
pka 6.52±0.10(Predicted)
color White to off-white

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22051 LPA2 Antagonist 1 ≥98% 1017606-66-4 1mg $236 2024-03-01 Buy
Cayman Chemical 22051 LPA2 Antagonist 1 ≥98% 1017606-66-4 5mg $395 2024-03-01 Buy
Cayman Chemical 22051 LPA2 Antagonist 1 ≥98% 1017606-66-4 10mg $656 2024-03-01 Buy
TRC N926243 N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine 1017606-66-4 5mg $350 2021-12-16 Buy
ChemScene CS-3103 LPA2antagonist1 99.12% 1017606-66-4 5mg $420 2021-12-16 Buy
Product number Packaging Price Buy
22051 1mg $236 Buy
22051 5mg $395 Buy
22051 10mg $656 Buy
N926243 5mg $350 Buy
CS-3103 5mg $420 Buy

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Chemical Properties,Uses,Production

Description

LPA2 antagonist 1 is an antagonist of lysophosphatidic acid receptor 2 (LPA2; IC50 = 17 nM). It is selective for LPA2 over LPA1 and LPA3 (IC50s = >50 μM). LPA2 antagonist 1 inhibits HGF-induced phosphorylation of ERK and proliferation of HCT116 colon cancer cells in a concentration-dependent manner.

Uses

N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine is a Lpa2 protein antagonists.

References

[1] HILARY P. BECK . Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18 3: Pages 1037-1041. DOI: 10.1016/j.bmcl.2007.12.024

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43339 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7552 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
Guangzhou QiYun Biotechnology Co., Ltd. 020-61288194 61288195 505721671@qq.com China 3866 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 8011 55
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58
LETOPHARM LIMITED 58
Guangzhou QiYun Biotechnology Co., Ltd. 58
Tianjin Kailiqi Biotechnology Co., Ltd. 55

View Lastest Price from Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LPA2 antagonist 1 pictures 2025-12-09 LPA2 antagonist 1
1017606-66-4
 US $463.00-117.00 / mg 99.85% 10g TargetMol Chemicals Inc.

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Spectrum

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-(1017606-66-4)1HNMR
Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- LPA2 antagonist 1 (S)-N-(1-(4-((3,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)propan-2-yl)-7-methylthieno[3,2-d]pyrimidin-4-amine N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine LPA2-IN-1 CS-1271 LPA-2 antagonist 1,LPA2 antagonist 1 1017606-66-4 C20H23Cl2N5O2S2