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WAY-151932

CAS No.
220460-92-4
Chemical Name:
WAY-151932
Synonyms
VNA-932;WAY-151932;WAY-VNA 932;WAY151932,WAY 151932;Methanone, [2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl-
CBNumber:
CB23175600
Molecular Formula:
C23H19ClN4O
Molecular Weight:
402.88
MDL Number:
MFCD05662330
MOL File:
220460-92-4.mol
Last updated:2023-05-21 10:59:17

WAY-151932 Properties

Boiling point 630.6±55.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 0.04±0.12(Predicted)
FDA UNII CC7IZ88XD2

WAY-151932 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-6661 WAY-151932 220460-92-4 1mg $550 2021-12-16 Buy
Product number Packaging Price Buy
CS-6661 1mg $550 Buy

WAY-151932 Chemical Properties,Uses,Production

Biological Activity

WAY-151932 is an antidiuretic hormone V2 receptor agonist with IC50 of 80.3 and 778 nM in human V2 and V1a binding assays, respectively.

in vitro

WAY-151932 (VNA-932) stimulates cAMP formation in LV2 cells expressing the hV 2 receptors in a dose-dependent manner with an EC 50 of 0.74±0.07 nM.

in vivo

Oral administration of WAY-151932 (VNA-932) to water-loaded conscious rats produces a dose-dependent decrease in urine volume (ED 50 =0.14 mg/kg, 2.5% starch in water vehicle) and a corresponding increase in osmolality without altering the urine electrolyte excretion profile.

target

IC50: 80.3 nM (human-V2 binding), 778 nM (human-V1a binding)

WAY-151932 Preparation Products And Raw materials

Raw materials

Preparation Products

WAY-151932 Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Shanghai Amico Chemicals Co. LTD 18019252918 sale@amkchem.com China 15014 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5019 58
WAY-151932 VNA-932 Methanone, [2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl- WAY-VNA 932 WAY151932,WAY 151932 220460-92-4