Diphlorethohydroxycarmalol
- CAS No.
- 138529-04-1
- Chemical Name:
- Diphlorethohydroxycarmalol
- Synonyms
- Diphlorethohydroxycarmalol;Diphlorethohydroxycarmalol （DPHC）;Dibenzo[b,e][1,4]dioxin-1,2,6,8-tetrol, 7-(3,5-dihydroxyphenoxy)-3-(2,4,6-trihydroxyphenoxy)-
- CBNumber:
- CB23284670
- Molecular Formula:
- C24H16O13
- Molecular Weight:
- 512.38
- MDL Number:
- MOL File:
- 138529-04-1.mol
Diphlorethohydroxycarmalol Chemical Properties,Uses,Production
Uses
Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1].
in vivo
The increase of postprandial blood glucose levels are significantly suppressed in the Diphlorethohydroxycarmalol-administered group than those in the streptozotocin-induced diabetic or normal mice. Moreover, the area under curve (AUC) is significantly reduced via Diphlorethohydroxycarmalol (100 mg/kg; p.o.) administration (2022 versus 2210 mmol x min/lL) in the diabetic mice as well as it delays absorption of dietary carbohydrates[1].
References
[1] Soo-Jin Heo, et al. Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent alpha-glucosidase and alpha-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice. Eur J Pharmacol. 2009 Aug 1;615(1-3):252-6. DOI:10.1016/j.ejphar.2009.05.017
Diphlorethohydroxycarmalol Preparation Products And Raw materials
Raw materials
Preparation Products
Diphlorethohydroxycarmalol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | China | 1860 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29257 | 58 |
| Supplier | Advantage |
|---|---|
| Aktin Chemicals, Inc. | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 60 |
| Aktin Chemicals, Inc. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
