Nicodicosapent
- CAS No.
- 1269181-69-2
- Chemical Name:
- Nicodicosapent
- Synonyms
- Nicodicosapent;3-Pyridinecarboxamide, N-[2-[[(5Z,8Z,11Z,14Z,17Z)-1-oxo-5,8,11,14,17-eicosapentaen-1-yl]amino]ethyl]-
- CBNumber:
- CB23333738
- Molecular Formula:
- C28H39N3O2
- Molecular Weight:
- 449.63
- MDL Number:
- MFCD30747923
- MOL File:
- 1269181-69-2.mol
| Product description | Number | Pack Size | Price |
| Nicodicosapent 98.09% | CS-7484 | 2mg | $120 |
| Nicodicosapent 98.09% | CS-7484 | 5mg | $216 |
| Nicodicosapent 98.09% | CS-7484 | 10mg | $360 |
| Nicodicosapent 98.09% | CS-7484 | 50mg | $1080 |
| Nicodicosapent 98.09% | CS-7484 | 100mg | $1800 |
| Boiling point | 677.5±55.0 °C(Predicted) |
|---|---|
| Density | 1.013±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: ≥ 100 mg/mL (222.41 mM); Ethanol: 2 mg/mL (4.45 mM); Water: < 0.1 mg/mL (insoluble) |
| form | Solid |
| pka | 13.26±0.46(Predicted) |
| color | Light yellow to yellow |
| FDA UNII | 72995E50VA |
Nicodicosapent price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-7484 | Nicodicosapent 98.09% | 1269181-69-2 | 2mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-7484 | Nicodicosapent 98.09% | 1269181-69-2 | 5mg | $216 | 2021-12-16 | Buy |
| ChemScene | CS-7484 | Nicodicosapent 98.09% | 1269181-69-2 | 10mg | $360 | 2021-12-16 | Buy |
| ChemScene | CS-7484 | Nicodicosapent 98.09% | 1269181-69-2 | 50mg | $1080 | 2021-12-16 | Buy |
| ChemScene | CS-7484 | Nicodicosapent 98.09% | 1269181-69-2 | 100mg | $1800 | 2021-12-16 | Buy |
Nicodicosapent Chemical Properties,Uses,Production
Uses
Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.
in vivo
Nicodicosapent (100 mg/kg po) produces high plasma levels of nicotinuric acid in the plasma. ApoE*3-Leiden mice treated with Nicodicosapent show a significant reduction in PCSK9 levels, LDL particles including VLDL and LDL cholesterol, as well as plasma triglycerides[1].
References
[1] Vu CB, et al. Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid. J Med Chem. 2016 Feb 11;59(3):1217-31. DOI:10.1021/acs.jmedchem.5b01961
Nicodicosapent Preparation Products And Raw materials
Raw materials
Preparation Products
Nicodicosapent Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19961 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 18101056239 | 3193328036@qq.com | China | 29759 | 68 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16111 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
View Lastest Price from Nicodicosapent manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-09 | Nicodicosapent
1269181-69-2
|
US $94.00-897.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Nicodicosapent
1269181-69-2
- US $94.00-897.00 / mg
- TargetMol Chemicals Inc.
