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ChemicalBook >> CAS DataBase List >>2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Structure
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE structure
CAS No.
111686-79-4
Chemical Name:
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
Synonyms
pr934-423a;fpl12924aa;RemacemideHCl;REMACEMIDE HYDROCHLORIDE;2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride;2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE;2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl-;2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid
CBNumber:
CB2360100
Molecular Formula:
C17H21ClN2O
Molecular Weight:
304.82
MDL Number:
MFCD00882179
MOL File:
111686-79-4.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:09
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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Properties

Melting point 253-254°
storage temp. room temp
solubility H2O: >10mg/mL
form powder
color white to beige
Water Solubility Soluble to 100 mM in water
FDA UNII I1ST2B6HIM

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H318-H400
Precautionary statements  P273-P280-P301+P312+P330-P305+P351+P338+P310
Hazard Codes  Xn,N
Risk Statements  22-41-50/53
Safety Statements  26-39-45-60-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  AB4349500
Toxicity LD50 (calculated as base) in rats (mg/kg): ~50 i.v., ~900 orally (Muir, Palmer)

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0335 Remacemide hydrochloride ≥98% (HPLC) 111686-79-4 10mg $144 2024-03-01 Buy
Sigma-Aldrich SML0335 Remacemide hydrochloride ≥98% (HPLC) 111686-79-4 50mg $540 2023-01-07 Buy
Tocris 1622 Remacemide hydrochloride ≥99%(HPLC) 111686-79-4 50 $592 2021-12-16 Buy
Tocris 1622 Remacemide hydrochloride ≥99%(HPLC) 111686-79-4 10 $140 2021-12-16 Buy
TRC R143450 Remacemide hydrochloride 111686-79-4 2.5mg $140 2021-12-16 Buy
Product number Packaging Price Buy
SML0335 10mg $144 Buy
SML0335 50mg $540 Buy
1622 50 $592 Buy
1622 10 $140 Buy
R143450 2.5mg $140 Buy

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Anticonvulsant (neuroprotective).

Biological Activity

Non-competitive NMDA receptor antagonist; blocks ion channel and allosteric modulatory site (IC 50 = 8-68 mM). Anticonvulsant in vivo and metabolizes to a more potent desglycine analog. Weakly blocks voltage-dependent Na + channels (IC 50 = 161 mM).

Biochem/physiol Actions

Remacemide HCl is a low affinity NMDA antagonist with anticonvulsant properties. Remacemide also been shown to block voltage-dependent sodium channels.

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Suppliers

Global( 27)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aromsyn Co., Ltd. 		+86-0571-85585865 +8613336024896 CB@aromsyn.com China 19185 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
SynAsst Chemical. 021-60343070 China 12742 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Hubei Xinyang Medical Technology Co., Ltd 15347293736 15347293736 2853117764@qq.com China 8854 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aromsyn Co., Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
SynAsst Chemical. 55
Sigma-Aldrich 80
EMMX Biotechnology LLC 60
Hubei Xinyang Medical Technology Co., Ltd 58
Energy Chemical 58

111686-79-4(2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE)Related Search:

2-AMINO-N-(TERT-BUTYL)ACETAMIDE HYDROCHLORIDE 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Ramacemide
REMACEMIDE HYDROCHLORIDE 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE RemacemideHCl 2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride 2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid 2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl- fpl12924aa pr934-423a 111686-79-4