ANTI-C-ERBB-2
- CAS No.
- Chemical Name:
- ANTI-C-ERBB-2
- Synonyms
- ANTI-NEU;Anti-NGL;Anti-TKR1;ANTI-HER-2;Anti-CD340;ANTI-ERBB-2;ANTI-C-ERB-2;ANTI-C-ERBB-2;Anti-FLJ93471;ANTI-HER-2, NEU
- CBNumber:
- CB2367785
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00239647
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Safety Statements | 23-24/25 |
|---|---|
| WGK Germany | - |
ANTI-C-ERBB-2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA001383 | Anti-ERBB2 antibody produced in rabbit Ab1, Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA001383 | Anti-ERBB2 antibody produced in rabbit Ab1, Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy | |
| Sigma-Aldrich | AMAB90628 | Monoclonal Anti-HER2 antibody produced in mouse Prestige Antibodies? Powered by Atlas Antibodies, clone CL0269, purified immunoglobulin, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy | |
| Sigma-Aldrich | AMAB90627 | Monoclonal Anti-HER2 antibody produced in mouse Prestige Antibodies? Powered by Atlas Antibodies, clone CL0268, purified immunoglobulin, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy | |
| Sigma-Aldrich | AMAB90628 | Monoclonal Anti-HER2 antibody produced in mouse Prestige Antibodies? Powered by Atlas Antibodies, clone CL0269, purified immunoglobulin, buffered aqueous glycerol solution | 25μL | $282 | 2023-06-20 | Buy |
ANTI-C-ERBB-2 Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
General Description
Human epidermal growth factor receptor 2 (HER2), also known as Erb-b2 receptor tyrosine kinase 2 (ErbB2), is encoded by the gene mapped to human chromosome 17. The encoded protein is a member of epidermal growth factor family. HER2 membrane protein is characterized with a cysteine-rich extracellular ligand-binding domain, a hydrophobic membrane spanning region and an intracellular tyrosine kinase domain.This protein does not have a ligand., It either forms heterodimers with other family members or homodimer with itself, when expressed at very high levels, to get activated. HER2 is expressed at low level in normal tissues, but at high level in breast cancer tissues.
Biochem/physiol Actions
Receptor tyrosine-protein kinase erbB-2 is a protein tyrosine kinase that is encoded by the gene ERBB2. It belongs to the epidermal growth factor (EGF) receptor family. The protein lacks a ligand binding domain and requires co-receptors for ligand binding. It functions as a transcriptional regulator by binding to cyclooxygenase enzyme COX-2 gene promoter. Overexpression of this gene has been observed in several types of cancer including breast and ovarian cancers. ErbB-2 enhances the EGF and NDF induced tyrosine phosphorylation of other ErbB family of receptor tyrosine kinases.
ANTI-C-ERBB-2 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-C-ERBB-2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |