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D-arabinitol

CAS No.
488-82-4
Chemical Name:
D-arabinitol
Synonyms
D-ARA-OL;D-Lyxitol;ARABINITOL;D(+)-ARABIT;D-ARABINITOL;arabinitol,D-;Arabinitol, D-;dextro-arabitol;D-(+)-ARABINITOL;ARABITOL, D-(+)-
CBNumber:
CB2424877
Molecular Formula:
C5H12O5
Molecular Weight:
152.15
MDL Number:
MFCD00004709
MOL File:
488-82-4.mol
MSDS File:
SDS
Last updated:2023-05-25 18:01:03

D-arabinitol Properties

Melting point 101-104 °C
alpha +10~+14゜(20℃/D)(c=5,Na2B4O7 soln.)
Boiling point 194.6°C (rough estimate)
Density 1.1497 (rough estimate)
refractive index 1.3960 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility H2O: 0.1 g/mL, clear, colorless
pka 13.24±0.20(Predicted)
form Fine Crystalline Powder
color White to off-white
Water Solubility Soluble in water (50 mg/ml).
Merck 14,762
BRN 1720520
LogP -3.774 (est)
CAS DataBase Reference 488-82-4(CAS DataBase Reference)
FDA UNII BOA443XF1X
EPA Substance Registry System D-Arabinitol (488-82-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280-P271
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
3-10
TSCA  Yes
HS Code  29054980
NFPA 704
1
1 0

D-arabinitol price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A3381 D-(+)-Arabitol ≥99% 488-82-4 25g $333 2024-03-01 Buy
Sigma-Aldrich A3381 D-(+)-Arabitol ≥99% 488-82-4 100g $1110 2024-03-01 Buy
TCI Chemical A0516 D-(+)-Arabitol >98.0%(GC) 488-82-4 1g $28 2024-03-01 Buy
TCI Chemical A0516 D-(+)-Arabitol >98.0%(GC) 488-82-4 25g $225 2024-03-01 Buy
Alfa Aesar A17801 D-(+)-Arabitol, 99% 488-82-4 5g $52.4 2024-03-01 Buy
Product number Packaging Price Buy
A3381 25g $333 Buy
A3381 100g $1110 Buy
A0516 1g $28 Buy
A0516 25g $225 Buy
A17801 5g $52.4 Buy

D-arabinitol Chemical Properties,Uses,Production

Description

D-arabinitol is a characteristic metabolic product of candida species. While candida ssp. produces exclusively D-arabinitol, L-arabinitol is developed by the body’s own metabolism. D-arabinitol serum levels increase if candida yeasts proliferate within the organism and cause invasive Candidiasis. Both D-arabinitol and L-arabinitol are present in normal urine, and can easily be measured by gas chromatography of urine samples collected on filter paper.

Chemical Properties

white to off-white fine crystalline powder

Occurrence

D-Arabinitol (lyxitol) is found in lichens; in a variety of fungi; in the urediospores of wheat stem rust; in the dried herbiage of the Peruvian shrub, pichi, along with D-mannitol, dulcitol, and perseitol; and in the avocado. It is formed by fermentation of glucose and in 40% yields using blackstrap molasses. D-Arabinitol is formed by catalytic hydrogenation of D-arabinose in the presence of Raney nickel and from the γ-lactones of D-arabinonic and D-lyxonic acids by reduction with sodium borohydride.

Uses

D-Arabitol, a rare sugar alcohol, is a substrate used to identify, differentiate and characterize enzyme such as the gluconobacter oxydans dehydrogenase(s), Gox2181, hyperthermophilic D-arabitol dehydrogenase from Thermotoga maritime and NAD-dependent D-arabitoldehydrogenase from acetic acid bacterium, Acetobacter suboxydans.

Definition

ChEBI: D-arabinitol is the D-enantiomer of arabinitol. It is an enantiomer of a L-arabinitol. It is a metabolite found in the aging mouse brain.

Biotechnological Applications

D-arabinitol detection
Another approach to the diagnosis of invasive candidosis involves the detection in serum or urine of a metabolite, D-arabinitol, which is produced by most of the medically important Candida species with the exception of C. krusei and perhaps C. glabrata. Various methods have been developed to measure D-arabinitol concentrations in human serum and urine, including enzymatic-fluorometric and enzymatic-colorimetric procedures. Because increased levels of arabinitol are also found in human body fluids when renal function is impaired, the results are reported as the D-arabinitol- creatinine ratio. Although several large studies have demonstrated that patients with candidaemia have ele- vated serum D-arabinitol- creatinine ratios, this approach has still to achieve widespread clinical use.

Purification Methods

This pentol, which occurs in lichens and fungi, is purified by recrystallisation from 90% EtOH or MeOH. [Ashina & Yamagita Chem Ber 67 801 1934, derivarives: Nakagawa et al. Bull Chem Soc Jpn 40 2150 1967, Prince & Reichstein Helv Chim Acta 20 101 1937, Hough & Theobald Methods in Carbohydrate Chemistry I 94 1962, Academic Press, Beilstein 1 IV 2832.]

D-arabinitol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from D-arabinitol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D-arabinitol pictures 2023-02-08 D-arabinitol
488-82-4
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
 D-ARABINITOL pictures 2019-07-06 D-ARABINITOL
488-82-4
US $8.00 / kg 1kg 99% 10MT Career Henan Chemical Co
  • D-arabinitol pictures
  • D-arabinitol
    488-82-4
  • US $0.00 / KG
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
D-ARA-OL D(+)-ARABIT D-(+)-ARABINITOL D-ARABINITOL ARABITOL, D-(+)- ARABINITOL d-[4,5-13C2]arabinitol D-Arabitol, 99% 5GR (+)-Arabitol, D-(+)-Arabitol, D-Arabinitol (2R,4R)-1,2,3,4,5-Pentanepentol D-Lyxitol Arabinitol, D- arabinitol,D- D-PLUS-ARABITOL CRYSTALLINE D-(+)-Arabitol,99% (2R,4R)-pentane-1,2,3,4,5-pentol (2R,4R)-Pentane-1,2,3,4,5-pentaol D-arabinose alcohol D-(+)-Arabitol > D-(+)-Arabitol Solution, 100μg/mL D-ARABINITOL USP/EP/BP dextro-arabitol D(+)Arabitol (D-Arabinitol) extrapure 99% 488-82-4 Arabinose Sugar Alcohols Sugars Monosaccharides Specialty Synthesis Carbohydrate Synthesis MonosaccharideSpecialty Synthesis Carbohydrate Synthesis Carbohydrates Carbohydrates A to Carbohydrates A-CBiochemicals and Reagents Monosaccharides Sugars, Carbohydrates & Glucosides Arabinose Biochemistry Sugar Alcohols Sugars Dextrins、Sugar & Carbohydrates